Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KEAP1 | Q14145 | 2/20 | 0.42 |
| ▸ | NFE2L2 | Q16236 | 2/20 | 0.42 |
| ▸ | PPARG | P37231 | 5/20 | 0.41 |
| ▸ | PPARA | Q07869 | 2/20 | 0.41 |
| ▸ | PTGDR2 | Q9Y5Y4 | 6/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.40 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.39 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.39 |
| ▸ | KCNQ3 | O43525 | 1/20 | 0.38 |
| ▸ | KCNQ2 | O43526 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16348403 | 0.84 | PPARA (0.54) | KEAP1NFE2L2PPARGPPARAPTGDR2 | |
| SCHEMBL13522853 | 0.80 | PPARG (0.43) | KEAP1NFE2L2PPARGPPARAPTGDR2 | |
| SCHEMBL13522832 | 0.80 | PPARG (0.43) | KEAP1NFE2L2PPARGPPARAPTGDR2 | |
| SCHEMBL13522855 | 0.80 | PPARG (0.43) | KEAP1NFE2L2PPARGPPARAPTGDR2 | |
| SCHEMBL13522830 | 0.77 | P2RY14 (0.43) | KEAP1NFE2L2PPARGPPARAKDM4E | |
| SCHEMBL13522860 | 0.75 | P2RY14 (0.42) | KEAP1NFE2L2PPARGPPARAPTGDR2 | |
| SCHEMBL13522827 | 0.75 | P2RY14 (0.42) | KEAP1NFE2L2PPARGPPARAPTGDR2 | |
| SCHEMBL13522840 | 0.74 | MAPT (0.43) | PPARGPTGDR2KDM4E | |
| SCHEMBL13522833 | 0.74 | PPARG (0.52) | PPARGPPARAPTGDR2 | |
| SCHEMBL13523039 | 0.74 | THRB (0.43) | PPARGPPARAKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7642358-B2 | Substituted phenylacetic acids | METABOLEX, INC. (US) | 2010-01-05 | — | — | US | disclosed |
| US-7642358-B2 | Substituted phenylacetic acids | METABOLEX, INC. (US) | 2010-01-05 | — | — | US | disclosed |