Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 8/20 | 0.56 |
| ▸ | DRD4 | P21917 | 8/20 | 0.56 |
| ▸ | DRD3 | P35462 | 8/20 | 0.56 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.47 |
| ▸ | IDO1 | P14902 | 1/20 | 0.38 |
| ▸ | MGAM | O43451 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | SI | P14410 | 1/20 | 0.37 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 4/20 | 0.36 |
| ▸ | GFER | P55789 | 3/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | PPARG | P37231 | 1/20 | 0.36 |
| ▸ | NCOA2 | Q15596 | 1/20 | 0.36 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.36 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 3/20 | 0.36 |
| ▸ | HTT | P42858 | 2/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16348383 | 0.85 | DRD2 (0.56) | DRD2DRD4DRD3IDO1MGAM | |
| SCHEMBL16348343 | 0.84 | PTPN11 (0.48) | DRD2DRD4DRD3PTPN11IDO1 | |
| SCHEMBL28524363 | 0.78 | PTPN11 (0.45) | DRD2DRD4DRD3PTPN11MAPT | |
| SCHEMBL2225496 | 0.74 | HDAC1 (0.47) | DRD2DRD4DRD3PTPN11MAPT | |
| SCHEMBL27809529 | 0.72 | MAPT (0.53) | DRD2DRD4DRD3MAPTGFER | |
| SCHEMBL6965803 | 0.72 | HDAC1 (0.50) | DRD2DRD4DRD3PTPN11GAA | |
| SCHEMBL28330296 | 0.71 | PIK3R1 (0.36) | DRD2DRD4DRD3PTPN11MAPT | |
| SCHEMBL28331654 | 0.71 | PIK3R1 (0.36) | DRD2DRD4DRD3PTPN11MAPT | |
| SCHEMBL3070107 | 0.71 | PTPN11 (0.50) | DRD2DRD4DRD3PTPN11MAPT | |
| SCHEMBL14060940 | 0.69 | PTPN11 (0.54) | PTPN11 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7642358-B2 | Substituted phenylacetic acids | METABOLEX, INC. (US) | 2010-01-05 | — | — | US | disclosed |
| US-7642358-B2 | Substituted phenylacetic acids | METABOLEX, INC. (US) | 2010-01-05 | — | — | US | disclosed |