Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARA | Q07869 | 3/20 | 0.41 |
| ▸ | PPARG | P37231 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.41 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.40 |
| ▸ | DRD2 | P14416 | 6/20 | 0.39 |
| ▸ | DRD4 | P21917 | 6/20 | 0.39 |
| ▸ | DRD3 | P35462 | 6/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | CTSA | P10619 | 2/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | F9 | P00740 | 1/20 | 0.36 |
| ▸ | F10 | P00742 | 1/20 | 0.36 |
| ▸ | PLAU | P00749 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16348439 | 0.90 | PPARA (0.52) | PPARAPPARGALDH1A1NPSR1L3MBTL1 | |
| SCHEMBL16348390 | 0.83 | PPARA (0.49) | PPARAPPARGALDH1A1NPSR1L3MBTL1 | |
| SCHEMBL16348355 | 0.80 | KMT2A (0.45) | PPARAPPARGALDH1A1NPSR1L3MBTL1 | |
| SCHEMBL16348377 | 0.80 | PPARA (0.47) | PPARAPPARGALDH1A1NPSR1L3MBTL1 | |
| SCHEMBL16348437 | 0.80 | PPARA (0.47) | PPARAPPARGPTGDR2DRD2DRD4 | |
| SCHEMBL16348391 | 0.78 | PPARG (0.48) | PPARAPPARGPTGDR2DRD2DRD4 | |
| SCHEMBL16348403 | 0.78 | PPARA (0.54) | PPARAPPARGALDH1A1NPSR1L3MBTL1 | |
| SCHEMBL16348442 | 0.77 | PPARA (0.44) | PPARAPPARGPTGDR2KMT2A | |
| SCHEMBL13523077 | 0.76 | SIRT1 (0.48) | NPSR1LMNAMAPTTDP1 | |
| SCHEMBL16348401 | 0.75 | PPARG (0.47) | PPARAPPARGALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7642358-B2 | Substituted phenylacetic acids | METABOLEX, INC. (US) | 2010-01-05 | — | — | US | disclosed |
| US-7642358-B2 | Substituted phenylacetic acids | METABOLEX, INC. (US) | 2010-01-05 | — | — | US | disclosed |