Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 5/20 | 0.47 |
| ▸ | PPARA | Q07869 | 2/20 | 0.47 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | CASP3 | P42574 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.39 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.39 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.39 |
| ▸ | GRM7 | Q14831 | 1/20 | 0.38 |
| ▸ | DHODH | Q02127 | 2/20 | 0.36 |
| ▸ | SMO | Q99835 | 2/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | CNR1 | P21554 | 2/20 | 0.34 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.34 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.34 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16348391 | 0.77 | PPARG (0.48) | PPARGPPARAMEN1POLBCASP3 | |
| SCHEMBL13523037 | 0.77 | PPARG (0.49) | PPARGPPARAMEN1POLBCASP3 | |
| SCHEMBL16348403 | 0.76 | PPARA (0.54) | PPARGPPARAMEN1POLBCASP3 | |
| SCHEMBL16348401 | 0.76 | PPARG (0.47) | PPARGPPARA | |
| SCHEMBL16348399 | 0.76 | PPARG (0.47) | PPARGPPARA | |
| SCHEMBL16348439 | 0.75 | PPARA (0.52) | PPARGPPARAMEN1POLBCASP3 | |
| SCHEMBL16348353 | 0.75 | PPARG (0.55) | PPARGPPARAMEN1POLBCASP3 | |
| SCHEMBL16348373 | 0.75 | PPARG (0.55) | PPARGPPARAMEN1POLBCASP3 | |
| SCHEMBL16348436 | 0.74 | LMNA (0.47) | MCL1MEN1KMT2AGRM7SMO | |
| SCHEMBL13523059 | 0.73 | PPARG (0.48) | PPARGPPARAMEN1POLBCASP3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7642358-B2 | Substituted phenylacetic acids | METABOLEX, INC. (US) | 2010-01-05 | — | — | US | disclosed |
| US-7642358-B2 | Substituted phenylacetic acids | METABOLEX, INC. (US) | 2010-01-05 | — | — | US | disclosed |