Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | USP2 | O75604 | 1/20 | 0.36 |
| ▸ | PRNP | P04156 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | PPARG | P37231 | 1/20 | 0.36 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.36 |
| ▸ | NCOA2 | Q15596 | 1/20 | 0.36 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | AGPAT2 | O15120 | 9/20 | 0.34 |
| ▸ | IDO1 | P14902 | 3/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.30 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
| ▸ | STAT3 | P40763 | 1/20 | 0.30 |
| ▸ | RAB9A | P51151 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13523180 | 0.84 | HPGD (0.31) | HPGD | |
| SCHEMBL28120093 | 0.75 | JAK2 (0.39) | KDM4EALDH1A1HPGDTSHRSMN1; SMN2 | |
| SCHEMBL2989844 | 0.74 | S1PR4 (0.42) | HPGDTDP1NPC1STAT3RAB9A | |
| SCHEMBL15746726 | 0.73 | PDE4A (0.32) | HPGDTSHRSMN1; SMN2 | |
| SCHEMBL31039366 | 0.72 | IDO1 (0.38) | KDM4EALDH1A1USP2PRNPHPGD | |
| SCHEMBL15079440 | 0.72 | IDO1 (0.58) | AGPAT2IDO1F7F3DYRK1A | |
| SCHEMBL12378188 | 0.72 | CYP1A2 (0.43) | KDM4EALDH1A1NPSR1NPC1TSHR | |
| SCHEMBL21056991 | 0.72 | TSHR (0.57) | KDM4EALDH1A1HPGDGAATSHR | |
| SCHEMBL21056993 | 0.72 | TSHR (0.57) | KDM4EALDH1A1HPGDGAATSHR | |
| SCHEMBL11624239 | 0.72 | IDO1 (0.56) | ALDH1A1HPGDRXFP1AGPAT2IDO1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7642358-B2 | Substituted phenylacetic acids | METABOLEX, INC. (US) | 2010-01-05 | — | — | US | disclosed |