Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDO1 | P14902 | 4/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.42 |
| ▸ | HTR2B | P41595 | 1/20 | 0.42 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.42 |
| ▸ | AGPAT2 | O15120 | 1/20 | 0.40 |
| ▸ | F7 | P08709 | 1/20 | 0.39 |
| ▸ | F3 | P13726 | 1/20 | 0.39 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.38 |
| ▸ | PKM | P14618 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | CNR2 | P34972 | 1/20 | 0.38 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.36 |
| ▸ | ALPL | P05186 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3846339 | 0.85 | ALPL (0.49) | IDO1F7F3DYRK1AMAPT | |
| SCHEMBL14400038 | 0.81 | IDO1 (0.58) | IDO1ALDH1A1HTR2BPDE4DF7 | |
| SCHEMBL31039366 | 0.81 | IDO1 (0.38) | IDO1ALDH1A1RXFP1F7F3 | |
| SCHEMBL6031031 | 0.81 | IDO1 (0.58) | IDO1ALDH1A1AGPAT2MAPTMEN1 | |
| SCHEMBL27660921 | 0.81 | IDO1 (0.38) | IDO1MAPTMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL15079440 | 0.81 | IDO1 (0.58) | IDO1AGPAT2F7F3DYRK1A | |
| SCHEMBL12096419 | 0.79 | HSP90AA1 (0.54) | IDO1ALDH1A1MAPTMEN1HPGD | |
| SCHEMBL25299734 | 0.78 | F7 (0.37) | IDO1F7F3DYRK1AMAPT | |
| SCHEMBL3846744 | 0.78 | KMO (0.44) | IDO1F7F3DYRK1AALPL | |
| SCHEMBL26915263 | 0.78 | KDM1A (0.45) | IDO1AGPAT2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4072498-A | HERBICIDES | THE UPJOHN COMPANY (US) | 1978-02-07 | — | — | US | disclosed |