Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARA | Q07869 | 7/20 | 0.43 |
| ▸ | PPARG | P37231 | 6/20 | 0.43 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.35 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.35 |
| ▸ | PTGER1 | P34995 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | CASP3 | P42574 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.34 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.34 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.34 |
| ▸ | TSPO | P30536 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16348442 | 0.96 | PPARA (0.44) | PPARAPPARGFFAR1PTGER1MEN1 | |
| SCHEMBL16348401 | 0.91 | PPARG (0.47) | PPARAPPARGFFAR1KDM4E | |
| SCHEMBL16348402 | 0.90 | PPARA (0.37) | PPARAPPARGFFAR1PTGER1 | |
| SCHEMBL16348391 | 0.87 | PPARG (0.48) | PPARAPPARGFFAR1MEN1POLB | |
| SCHEMBL16348377 | 0.86 | PPARA (0.47) | PPARAPPARGFFAR1KDM4EMEN1 | |
| SCHEMBL16348399 | 0.85 | PPARG (0.47) | PPARAPPARGFFAR1 | |
| SCHEMBL16348345 | 0.83 | PPARA (0.41) | PPARAPPARGFFAR1MEN1POLB | |
| SCHEMBL16348390 | 0.82 | PPARA (0.49) | PPARAPPARGFFAR1KDM4EMEN1 | |
| SCHEMBL16348437 | 0.81 | PPARA (0.47) | PPARAPPARGKDM4EMEN1POLB | |
| SCHEMBL16348439 | 0.79 | PPARA (0.52) | PPARAPPARGPTGER1KDM4EMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7642358-B2 | Substituted phenylacetic acids | METABOLEX, INC. (US) | 2010-01-05 | — | — | US | disclosed |
| US-7642358-B2 | Substituted phenylacetic acids | METABOLEX, INC. (US) | 2010-01-05 | — | — | US | disclosed |