Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARA | Q07869 | 9/20 | 0.37 |
| ▸ | PPARG | P37231 | 8/20 | 0.37 |
| ▸ | DRD2 | P14416 | 5/20 | 0.36 |
| ▸ | DRD4 | P21917 | 5/20 | 0.36 |
| ▸ | DRD3 | P35462 | 5/20 | 0.36 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.35 |
| ▸ | PTGER1 | P34995 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16348442 | 0.93 | PPARA (0.44) | PPARAPPARGFFAR1PTGER1 | |
| SCHEMBL16348398 | 0.90 | PPARA (0.43) | PPARAPPARGFFAR1PTGER1 | |
| SCHEMBL16348345 | 0.86 | PPARA (0.41) | PPARAPPARGFFAR1 | |
| SCHEMBL16348377 | 0.84 | PPARA (0.47) | PPARAPPARGDRD2DRD4DRD3 | |
| SCHEMBL16348401 | 0.81 | PPARG (0.47) | PPARAPPARGFFAR1 | |
| SCHEMBL16348441 | 0.81 | PPARG (0.43) | PPARAPPARG | |
| SCHEMBL16348440 | 0.81 | PPARA (0.41) | PPARAPPARGFFAR1 | |
| SCHEMBL16348390 | 0.80 | PPARA (0.49) | PPARAPPARGDRD2DRD4DRD3 | |
| SCHEMBL16348437 | 0.79 | PPARA (0.47) | PPARAPPARGDRD2DRD4DRD3 | |
| SCHEMBL16348391 | 0.77 | PPARG (0.48) | PPARAPPARGDRD2DRD4DRD3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7642358-B2 | Substituted phenylacetic acids | METABOLEX, INC. (US) | 2010-01-05 | — | — | US | disclosed |
| US-7642358-B2 | Substituted phenylacetic acids | METABOLEX, INC. (US) | 2010-01-05 | — | — | US | disclosed |