⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9407525 | 0.87 | TSHR (0.33) | — | |
| SCHEMBL19407254 | 0.86 | TSHR (0.32) | — | |
| SCHEMBL13661597 | 0.86 | TSHR (0.32) | — | |
| SCHEMBL4915543 | 0.84 | TSHR (0.30) | — | |
| SCHEMBL11089087 | 0.82 | — | — | |
| SCHEMBL4916655 | 0.81 | ALDH1A1 (0.30) | — | |
| SCHEMBL5038322 | 0.81 | ALDH1A1 (0.30) | — | |
| SCHEMBL4909539 | 0.81 | ALDH1A1 (0.30) | — | |
| SCHEMBL7962706 | 0.81 | TSHR (0.54) | — | |
| SCHEMBL20834970 | 0.79 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 35 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2782921-B1 | ORGANIC TUNGSTEN COMPLEXES | VANDERBILT CHEMICALS LLC (US) | 2018-05-02 | — | — | EP | disclosed |
| US-9908892-B2 | Melampomagnolide B derivatives | BIOVENTURES, LLC (US) | 2018-03-06 | — | — | US | disclosed |
| EP-2782921-A1 | ORGANIC TUNGSTEN COMPLEXES | Vanderbilt Chemicals, LLC (US) | 2014-10-01 | — | — | EP | disclosed |
| CN-103958536-A | Organic tungsten complexes | VANDERBILT CHEMICALS LLC | 2014-07-30 | — | — | CN | disclosed |
| US-8669386-B2 | Organic tungsten complexes | VANDEBILT CHEMICALS, LLC (US) | 2014-03-11 | — | — | US | disclosed |
| WO-2013077948-A1 | ORGANIC TUNGSTEN COMPLEXES | VANDERBILT CHEMICALS, LLC. (US) | 2013-05-30 | — | — | WO | disclosed |
| US-20120165563-A1 | ORGANIC TUNGSTEN COMPLEXES | R.T. VANDERBILT COMPANY, INC. | 2012-06-28 | — | — | US | disclosed |
| EP-2217580-B1 | SUBSTITUTED TETRAZOLE COMPOUNDS AND USES THEREOF | ARQULE INC (US) | 2011-12-21 | — | — | EP | disclosed |
| US-7932279-B2 | Substituted tetrazole compounds and uses thereof | ARQULE, INC. (US) | 2011-04-26 | — | — | US | disclosed |
| EP-2217580-A2 | SUBSTITUTED TETRAZOLE COMPOUNDS AND USES THEREOF | ArQule, Inc. (US) | 2010-08-18 | — | — | EP | disclosed |
| EP-0637298-B1 | SUBSTITUTED CYCLOHEXENE-1,2-BICARBOXYLIC ACID DERIVATIVES AND RAW MATERIALS FOR PRODUCING THEM | BASF AG (DE) | 1999-03-31 | — | — | EP | disclosed |
| US-5817603-A | HERBICIDES | BASF AKTIENGESELLSCHAFT (DE) | 1998-10-06 | — | — | US | disclosed |
| US-5602074-A | HERBICIDES; PLANT DESICCATION, DEFOLIATION | BASF AKTIENGESELLSCHAFT (DE) | 1997-02-11 | — | — | US | disclosed |
| EP-0641321-A1 | SUBSTITUTED ISOINDOLONES | BASF Aktiengesellschaft (DE) | 1995-03-08 | — | — | EP | disclosed |
| EP-0637298-A1 | SUBSTITUTED CYCLOHEXENE-1,2-BICARBOXYLIC ACID DERIVATIVES AND RAW MATERIALS FOR PRODUCING THEM | BASF Aktiengesellschaft (DE) | 1995-02-08 | — | — | EP | disclosed |
| WO-1993024456-A1 | SUBSTITUTED ISOINDOLONES | BASF AKTIENGESELLSCHAFT (DE) | 1993-12-09 | — | — | WO | disclosed |
| WO-1993022280-A1 | SUBSTITUTED CYCLOHEXENE-1,2-BICARBOXYLIC ACID DERIVATIVES AND RAW MATERIALS FOR PRODUCING THEM | BASF AKTIENGESELLSCHAFT (DE) | 1993-11-11 | — | — | WO | disclosed |
| US-4728646-A | ANTITHROMBOTICS | DR. KARL THOMAE GMBH (DE) | 1988-03-01 | — | — | US | disclosed |
| US-4690923-A | ANTITHROMBOTICS | KARL THOMAE GMBH (DE) | 1987-09-01 | — | — | US | disclosed |
| US-4518596-A | Antithrombotic use of 2-(perhydro-1,4-diazino)-pyrimido (5,4,D)-pyrimidines | DR. KARL THOMAE GMBH (DE) | 1985-05-21 | — | — | US | disclosed |