SCHEMBL16348648

SCHEMBL16348648

[c]1ccc2c(c1)Cc1c[c]ccc1O2

nearest known ligand 0.46

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
MAOA P21397 1/20 0.46
MAOB P27338 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15062681 0.92 MAOA (0.45) MAOAMAOB
SCHEMBL194519 0.90 MAOA (0.65) MAOAMAOB
SCHEMBL3358107 0.83 MAOA (0.36) MAOAMAOB
SCHEMBL194121 0.77 MAOA (0.36) MAOAMAOB
SCHEMBL7789411 0.77 ABCC4 (0.46) MAOAMAOB
SCHEMBL195110 0.77 MAOA (0.65) MAOAMAOB
SCHEMBL4603443 0.74
SCHEMBL6038298 0.74
SCHEMBL3352688 0.73 TSHR (0.37) MAOB
SCHEMBL1452118 0.70

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9410016-B2 Aromatic polyacetals and articles comprising them DOW GLOBAL TECHNOLOGIES LLC (US) 2016-08-09 US disclosed
US-9063420-B2 Photoresist composition, coated substrate, and method of forming electronic device ROHM AND HAAS ELECTRONIC MATERIALS LLC (US) 2015-06-23 US disclosed
US-8962779-B2 Method of forming polyaryl polymers DOW GLOBAL TECHNOLOGIES LLC (US) 2015-02-24 US disclosed
US-20150031847-A1 METHOD OF FORMING POLYARYL POLYMERS DOW GLOBAL TECHNOLOGIES LLC 2015-01-29 US disclosed
US-20150025278-A1 AROMATIC POLYACETALS AND ARTICLES COMPRISING THEM U.S. BANK TRUST COMPANY, NATIONAL ASSOCIATION, AS NOTES COLLATERAL AGENT 2015-01-22 US disclosed
US-20150021289-A1 PHOTORESIST COMPOSITION, COATED SUBSTRATE, AND METHOD OF FORMING ELECTRONIC DEVICE U.S. BANK TRUST COMPANY, NATIONAL ASSOCIATION, AS NOTES COLLATERAL AGENT 2015-01-22 US disclosed
US-20150025262-A1 BIS(ARYL)ACETAL COMPOUNDS U.S. BANK TRUST COMPANY, NATIONAL ASSOCIATION, AS NOTES COLLATERAL AGENT 2015-01-22 US disclosed
US-8933239-B1 Bis(aryl)acetal compounds DOW GLOBAL TECHNOLOGIES LLC (US) 2015-01-13 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20150025262-A1 BIS(ARYL)ACETAL COMPOUNDS BOLA2; BOLA2B, TARS1, CBR1 MAOA 239/4885MAOB 175/4885
US-20150025278-A1 AROMATIC POLYACETALS AND ARTICLES COMPRISING THEM AR, PARP1, PARG MAOA 513/4885MAOB 1596/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.