Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACP3 | P15309 | 4/20 | 0.47 |
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 3/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.44 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.41 |
| ▸ | MEP1B | Q16820 | 2/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28899399 | 1.00 | ACP3 (0.47) | ACP3MAPTL3MBTL1MEN1KMT2A | |
| SCHEMBL28464084 | 0.86 | ACP3 (0.44) | ACP3MAPTL3MBTL1MEN1KMT2A | |
| SCHEMBL15721086 | 0.84 | KMT2A (0.44) | ACP3MAPTL3MBTL1MEN1KMT2A | |
| SCHEMBL28499340 | 0.82 | ACP3 (0.51) | ACP3MAPTMEN1KMT2ASIGMAR1 | |
| SCHEMBL4282571 | 0.81 | CA1 (0.46) | ALDH1A1 | |
| SCHEMBL4282703 | 0.81 | CA1 (0.46) | ALDH1A1 | |
| SCHEMBL27536452 | 0.81 | CA1 (0.46) | ALDH1A1 | |
| SCHEMBL106076 | 0.80 | MAPT (0.67) | MAPTL3MBTL1MEN1KMT2ASIGMAR1 | |
| SCHEMBL106075 | 0.80 | MAPT (0.67) | MAPTL3MBTL1MEN1KMT2ASIGMAR1 | |
| SCHEMBL914510 | 0.80 | MAPT (0.67) | MAPTL3MBTL1MEN1KMT2ASIGMAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8933053-B2 | Phosphoramidate derivatives of 5-fluoro-2′-deoxyuridine for use in the treatment of cancer | NUCANA BIOMED LIMITED (GB) | 2015-01-13 | — | — | US | disclosed |