SCHEMBL106076

SCHEMBL106076

COC(=O)[C@H](C)NCc1ccccc1

nearest known ligand 0.67

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
MAPT P10636 2/20 0.67
L3MBTL1 Q9Y468 1/20 0.67
KMT2A Q03164 3/20 0.56
MEN1 O00255 2/20 0.56
ATM Q13315 1/20 0.51
TRPM8 Q7Z2W7 1/20 0.51
SIGMAR1 Q99720 1/20 0.50
TSHR P16473 1/20 0.48
ALDH1A1 P00352 2/20 0.47
POLB P06746 1/20 0.47
MEP1B Q16820 2/20 0.47
THRB P10828 1/20 0.47
CYP2C9 P11712 1/20 0.47
CYP2C19 P33261 1/20 0.47
HSD17B10 Q99714 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL106075 1.00 MAPT (0.67) MAPTL3MBTL1KMT2AMEN1ATM
SCHEMBL914510 1.00 MAPT (0.67) MAPTL3MBTL1KMT2AMEN1ATM
Hydrochloric Acid SCHEMBL1604706 0.98 MAPT (0.65) MAPTL3MBTL1KMT2AMEN1ATM
Hydrochloric Acid SCHEMBL1604707 0.98 MAPT (0.65) MAPTL3MBTL1KMT2AMEN1ATM
SCHEMBL16838967 0.90 MAPT (0.56) MAPTL3MBTL1KMT2AMEN1ATM
SCHEMBL6376551 0.89 MAPT (0.67) MAPTL3MBTL1KMT2AMEN1ATM
SCHEMBL1878484 0.86 SMN1; SMN2 (0.53) MAPTL3MBTL1KMT2AMEN1SIGMAR1
SCHEMBL1878485 0.86 SMN1; SMN2 (0.53) MAPTL3MBTL1KMT2AMEN1SIGMAR1
SCHEMBL30929593 0.86 SMN1; SMN2 (0.53) MAPTL3MBTL1KMT2AMEN1SIGMAR1
Hydrochloric Acid SCHEMBL27396543 0.85 SMN1; SMN2 (0.51) MAPTL3MBTL1KMT2AMEN1SIGMAR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 153 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0105092-A2 A thrombolytic agent Amano Seiyaku Kabushiki Kaisha (JP) 1984-04-11 EP claimed
US-20260125378-A2 Heterocyclic Compounds BEONE MEDICINES I GMBH (CH) 2026-05-07 US disclosed
EP-4658650-A1 HETEROCYCLIC COMPOUNDS Beone Medicines I GmbH (CH) 2025-12-10 EP disclosed
US-20250353846-A1 Heterocyclic Compounds BEONE MEDICINES I GMBH (CH) 2025-11-20 US disclosed
EP-4021901-B1 SUBSTITUTED PYRIDOPYRIMIDINONYL COMPOUNDS USEFUL AS T CELL ACTIVATORS BRISTOL MYERS SQUIBB CO (US) 2025-09-24 EP disclosed
US-20240400563-A1 SUBSTITUTED PYRIDOPYRIMIDINONYL COMPOUNDS USEFUL AS T CELL ACTIVATORS BRISTOL-MYERS SQUIBB COMPANY 2024-12-05 US disclosed
EP-4457224-A1 HETEROCYCLIC COMPOUNDS BeiGene Switzerland GmbH (CH) 2024-11-06 EP disclosed
US-20240327417-A1 HETEROCYCLIC COMPOUNDS BEIGENE SWITZERLAND GMBH (CH) 2024-10-03 US disclosed
WO-2024160277-A1 HETEROCYCLIC COMPOUNDS BEIGENE, LTD. (KY) 2024-08-08 WO disclosed
CN-118451073-A Heterocyclic compounds 百济神州有限公司 2024-08-06 CN disclosed
EP-0393424-B1 Process for the preparation of 2,7-Diazabicyclo(3.3.O)octanes BAYER AG (DE) 1995-09-27 EP disclosed
US-5344942-A Enantiomorphs and induction CHEMIE LINZ GESELLSCHAFT M.B.H. (AT) 1994-09-06 US disclosed
US-5284855-A Broad-spectrum antibiotics; gramnegative and -positive bacteria, esp. Enterobacter BAYER AKTIENGESELLSCHAFT (DE) 1994-02-08 US disclosed
EP-0565969-A1 Tricyclic lactols, their use as resolving agents and processes for their production DSM Chemie Linz GmbH (AT) 1993-10-20 EP disclosed
US-5241076-A 1,4-diazatricyclo [6.3.0.0]undecanes BAYER AKTIENGESELLSCHAFT (DE) 1993-08-31 US disclosed
US-5202337-A Antibacterial agent, feed additive BAYER AKTIENGESELLSCHAFT (DE) 1993-04-13 US disclosed
US-5177210-A Preparation of 2,7-diazabicyclo(3.3.0)octanes BAYER AKTIENGESELLSCHAFT (DE) 1993-01-05 US disclosed
EP-0481274-A1 7-(2,7-Diazabicyclo[3.3.0]octyl)-3-quinolone- and -naphthyridonecarboxylic acid derivatives BAYER AG (DE) 1992-04-22 EP disclosed
US-5071999-A Preparation of 2,7-diazabicyclo[3.3.0]octanes BAYER AKTIENGESELLSCHAFT (DE) 1991-12-10 US disclosed
EP-0393424-A2 Process for the preparation of 2,7-Diazabicyclo(3.3.O)octanes BAYER AG (DE) 1990-10-24 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260125378-A2 Heterocyclic Compounds NFATC1, CD4, MALT1 MAPT 3357/4885L3MBTL1 3828/4885KMT2A 3652/4885
US-20240400563-A1 SUBSTITUTED PYRIDOPYRIMIDINONYL COMPOUNDS USEFUL AS T CELL ACTIVATORS DGKZ, DGKA, DGKG MAPT 4503/4885L3MBTL1 3558/4885KMT2A 2162/4885
US-20240327417-A1 HETEROCYCLIC COMPOUNDS NFATC1, CD4, ACIN1 MAPT 3912/4885L3MBTL1 4624/4885KMT2A 2438/4885
US-20250353846-A1 Heterocyclic Compounds NFATC1, CD4, ACIN1 MAPT 3912/4885L3MBTL1 4624/4885KMT2A 2438/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.