SCHEMBL16349703

CC(=O)[C@H](CS)NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](CSC(C)(C)C)NC(=O)[C@H](CC(=O)O)NC(=O)CNC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@H](CSC(C)(C)C)NC(=O)[C@H](CCCCN)NC(=O)CCl

nearest known ligand 0.50

Predicted protein targets (top 3)

	gene	UniProt	supporting neighbours	confidence
▸	IL23R	Q5VWK5	13/20	0.50

▸	OPRL1	P41146	3/20	0.47

▸	TFPI	P10646	1/20	0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compound	similarity	top predicted	shared targets
SCHEMBL23057565	0.97	IL23R (0.51)	IL23ROPRL1TFPI
SCHEMBL10046542	0.97	IL23R (0.51)	IL23ROPRL1TFPI
SCHEMBL12082890	0.94	IL23R (0.50)	IL23ROPRL1TFPI
SCHEMBL22003315	0.93	IL23R (0.48)	IL23ROPRL1TFPI
SCHEMBL22382220	0.92	IL23R (0.51)	IL23ROPRL1
SCHEMBL13703199	0.92	IL23R (0.51)	IL23ROPRL1
SCHEMBL31181281	0.91	IL23R (0.50)	IL23ROPRL1TFPI
SCHEMBL13659872	0.91	IL23R (0.52)	IL23R
SCHEMBL13870329	0.91	IL23R (0.54)	IL23R
SCHEMBL10046332	0.91	IL23R (0.52)	IL23R

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

Patent	Title	Assignee	Published	Priority	Filing	Country	Status
US-7521419-B2	Peptide-based compounds	GE HEALTHCARE AS (NO)	2009-04-21	—	—	US	disclosed