SCHEMBL10046542

SCHEMBL10046542

CC(C)(C)SC[C@H](NC(=O)[C@H](CCCCN)NC(=O)CCl)C(=O)N[C@@H](CCCNC(=N)N)C(=O)NCC(=O)N[C@@H](CC(=O)O)C(=O)N[C@@H](CSC(C)(C)C)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](CS)C(N)=O

nearest known ligand 0.51

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
▸ IL23R Q5VWK5 13/20 0.51
▸ OPRL1 P41146 3/20 0.48
▸ TFPI P10646 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23057565 1.00 IL23R (0.51) IL23ROPRL1TFPI
SCHEMBL16349703 0.97 IL23R (0.50) IL23ROPRL1TFPI
SCHEMBL22003315 0.96 IL23R (0.48) IL23ROPRL1TFPI
SCHEMBL12082890 0.95 IL23R (0.50) IL23ROPRL1TFPI
SCHEMBL31181281 0.94 IL23R (0.50) IL23ROPRL1TFPI
SCHEMBL13703199 0.93 IL23R (0.51) IL23ROPRL1
SCHEMBL22382220 0.93 IL23R (0.51) IL23ROPRL1
SCHEMBL13659872 0.92 IL23R (0.52) IL23R
SCHEMBL13870329 0.92 IL23R (0.54) IL23R
SCHEMBL10046332 0.92 IL23R (0.52) IL23R

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2025233638-A1 RADIOPHARMACEUTICAL IMAGING METHOD OF ADENOMYOSIS SERAC HEALTHCARE LTD (GB) 2025-11-13 — — WO disclosed
US-20250186633-A1 METHODS FOR IMAGING INTEGRIN EXPRESSION AND FOR IMAGING SITES OF ENDOMETRIOSIS SERAC HEALTHCARE LTD (GB) 2025-06-12 — — US disclosed
EP-4486396-A1 METHODS FOR IMAGING INTEGRIN EXPRESSION AND FOR IMAGING SITES OF ENDOMETRIOSIS Serac Healthcare Ltd (GB) 2025-01-08 — — EP disclosed
WO-2023166305-A1 METHODS FOR IMAGING INTEGRIN EXPRESSION AND FOR IMAGING SITES OF ENDOMETRIOSIS SERAC HEALTHCARE LTD (GB) 2023-09-07 — — WO disclosed
US-11723991-B2 Radiopharmaceutical compositions SERAC HEALTHCARE LIMITED (GB) 2023-08-15 — — US disclosed
US-10758635-B2 Radiopharmaceutical compositions SERAC HEALTHCARE LIMITED (GB) 2020-09-01 — — US disclosed
US-20130129623-A1 RADIOPHARMACEUTICAL COMPOSITIONS GE HEALTHCARE LIMTED (GB) 2013-05-23 — — US disclosed
US-8299030-B2 Peptide-based compounds GE HEALTHCARE LIMITED (GB) 2012-10-30 — — US disclosed
US-20120020882-A1 PEPTIDE-BASED COMPOUNDS GE HEALTHCARE AS (NO) 2012-01-26 — — US disclosed
US-7994134-B2 Peptide-based compounds GE HEALTHCARE AS (NO) 2011-08-09 — — US disclosed
US-7994134-B2 Peptide-based compounds GE HEALTHCARE AS (NO) 2011-08-09 — — US disclosed
US-20090203584-A1 Peptide-based Compounds GE HEALTHCARE LIMITED (GB) 2009-08-13 — — US disclosed
US-20090203584-A1 Peptide-based Compounds GE HEALTHCARE LIMITED (GB) 2009-08-13 — — US disclosed
US-7521419-B2 Peptide-based compounds GE HEALTHCARE AS (NO) 2009-04-21 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090203584-A1 Peptide-based Compounds ITGB3, ITGAV, SELPLG IL23R 973/4885OPRL1 541/4885TFPI 717/4885
US-11723991-B2 Radiopharmaceutical compositions TYMP, KIT, CHEK1 IL23R 2328/4885OPRL1 2460/4885TFPI 3207/4885
US-20250186633-A1 METHODS FOR IMAGING INTEGRIN EXPRESSION AND FOR IMAGING SITES OF ENDOMETRIOSIS ITGB3, ITGB5, ITGAV IL23R 1584/4885OPRL1 537/4885TFPI 1272/4885
US-10758635-B2 Radiopharmaceutical compositions TYMP, KIT, CHEK1 IL23R 2324/4885OPRL1 2633/4885TFPI 3310/4885
US-20120020882-A1 PEPTIDE-BASED COMPOUNDS ITGB3, ITGAV, SELPLG IL23R 973/4885OPRL1 541/4885TFPI 717/4885
US-20130129623-A1 RADIOPHARMACEUTICAL COMPOSITIONS TYMP, KIT, CHEK1 IL23R 2324/4885OPRL1 2633/4885TFPI 3310/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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