Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NAAA | Q02083 | 2/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16349813 | 1.00 | NAAA (0.31) | NAAAGAA | |
| SCHEMBL8291448 | 0.95 | NAAA (0.30) | NAAA | |
| SCHEMBL16349736 | 0.89 | NAAA (0.30) | NAAA | |
| SCHEMBL16349817 | 0.89 | NAAA (0.30) | NAAA | |
| SCHEMBL16315715 | 0.87 | GAA (0.35) | GAA | |
| SCHEMBL16349581 | 0.87 | GAA (0.35) | GAA | |
| SCHEMBL16349734 | 0.87 | GAA (0.35) | GAA | |
| SCHEMBL16349814 | 0.87 | — | — | |
| SCHEMBL16349801 | 0.87 | — | — | |
| SCHEMBL13685065 | 0.83 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7592419-B2 | Macrocyclic inhibitors of hepatitis C virus NS3-serine protease | SCHERING CORPORATION (US) | 2009-09-22 | — | — | US | disclosed |