Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FOLH1 | Q04609 | 8/20 | 0.59 |
| ▸ | PKM | P14618 | 2/20 | 0.53 |
| ▸ | PRSS1 | P07477 | 2/20 | 0.52 |
| ▸ | PRSS2 | P07478 | 2/20 | 0.52 |
| ▸ | PRSS3 | P35030 | 2/20 | 0.52 |
| ▸ | TPSAB1 | Q15661 | 2/20 | 0.52 |
| ▸ | F2 | P00734 | 1/20 | 0.52 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.52 |
| ▸ | PLG | P00747 | 1/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.48 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.48 |
| ▸ | KDM2A | Q9Y2K7 | 1/20 | 0.48 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.47 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.47 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.47 |
| ▸ | CNR1 | P21554 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8115912 | 0.92 | FOLH1 (0.61) | FOLH1PKMPRSS1PRSS2PRSS3 | |
| SCHEMBL8106640 | 0.86 | FOLH1 (0.54) | FOLH1PKMPRSS1PRSS2PRSS3 | |
| SCHEMBL24601548 | 0.86 | FOLH1 (0.70) | FOLH1PKMPRSS1PRSS2PRSS3 | |
| SCHEMBL16408402 | 0.86 | FOLH1 (0.58) | FOLH1PKMPRSS1PRSS2PRSS3 | |
| SCHEMBL12767763 | 0.85 | FOLH1 (0.61) | FOLH1PKMPRSS1PRSS2PRSS3 | |
| SCHEMBL12147642 | 0.85 | FOLH1 (0.61) | FOLH1PKMPRSS1PRSS2PRSS3 | |
| SCHEMBL14500455 | 0.85 | FOLH1 (0.59) | FOLH1PKMPRSS1PRSS2PRSS3 | |
| SCHEMBL24601734 | 0.85 | FOLH1 (0.70) | FOLH1PKMPRSS1PRSS2PRSS3 | |
| SCHEMBL24601730 | 0.85 | FOLH1 (0.70) | FOLH1PKMPRSS1PRSS2PRSS3 | |
| SCHEMBL24220333 | 0.84 | FOLH1 (0.68) | FOLH1PKMPRSS1PRSS2PRSS3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7910088-B2 | Multivalent constructs for therapeutic and diagnostic applications | BRACCO SUISSE SA (CH) | 2011-03-22 | — | — | US | disclosed |