Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GLP1R | P43220 | 8/20 | 0.65 |
| ▸ | SIRT6 | Q8N6T7 | 1/20 | 0.54 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.54 |
| ▸ | TLR2 | O60603 | 3/20 | 0.53 |
| ▸ | NMT2 | O60551 | 2/20 | 0.53 |
| ▸ | NMT1 | P30419 | 2/20 | 0.53 |
| ▸ | LPAR3 | Q9UBY5 | 4/20 | 0.50 |
| ▸ | SLC6A5 | Q9Y345 | 1/20 | 0.50 |
| ▸ | LPAR1 | Q92633 | 2/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30094802 | 0.85 | GLP1R (0.59) | GLP1RSIRT6SIRT1TLR2NMT2 | |
| SCHEMBL23585008 | 0.84 | GLP1R (0.55) | GLP1RTLR2LPAR3LPAR1 | |
| SCHEMBL26348694 | 0.84 | GLP1R (0.66) | GLP1RTLR2LPAR3LPAR1 | |
| SCHEMBL20542815 | 0.84 | SIRT6 (0.76) | GLP1RSIRT6SIRT1TLR2NMT2 | |
| SCHEMBL20542882 | 0.84 | SIRT6 (0.76) | GLP1RSIRT6SIRT1TLR2NMT2 | |
| SCHEMBL20543067 | 0.84 | SIRT6 (0.76) | GLP1RSIRT6SIRT1TLR2NMT2 | |
| SCHEMBL20542884 | 0.84 | SIRT6 (0.76) | GLP1RSIRT6SIRT1TLR2NMT2 | |
| SCHEMBL20543083 | 0.84 | SIRT6 (0.76) | GLP1RSIRT6SIRT1TLR2NMT2 | |
| SCHEMBL20542968 | 0.84 | SIRT6 (0.76) | GLP1RSIRT6SIRT1TLR2NMT2 | |
| SCHEMBL23519401 | 0.84 | SIRT6 (0.76) | GLP1RSIRT6SIRT1TLR2NMT2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7351790-B2 | Peptide-based compounds | GE HEALTHCARE AS (NO) | 2008-04-01 | — | — | US | disclosed |