Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TUBB1 | Q9H4B7 | 2/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL58451 | 0.90 | TUBB1 (0.56) | TUBB1 | |
| SCHEMBL16350324 | 0.83 | TUBB1 (0.55) | TUBB1 | |
| SCHEMBL58045 | 0.83 | TUBB1 (0.56) | TUBB1 | |
| SCHEMBL10175741 | 0.80 | TUBB1 (0.45) | TUBB1 | |
| SCHEMBL58036 | 0.80 | TUBB1 (0.45) | TUBB1 | |
| SCHEMBL58962 | 0.79 | TUBB1 (0.68) | TUBB1 | |
| SCHEMBL16171261 | 0.79 | TUBB1 (0.60) | TUBB1 | |
| SCHEMBL58971 | 0.78 | TUBB1 (0.52) | TUBB1 | |
| SCHEMBL4378540 | 0.78 | TUBB1 (0.58) | TUBB1 | |
| SCHEMBL58037 | 0.78 | TUBB1 (0.58) | TUBB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7585976-B2 | Hemiasterlin derivatives and uses thereof | EISAI CO., LTD. (JP) | 2009-09-08 | — | — | US | disclosed |