Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP2 | P08253 | 2/20 | 0.52 |
| ▸ | ANPEP | P15144 | 2/20 | 0.52 |
| ▸ | DPP7 | Q9UHL4 | 5/20 | 0.36 |
| ▸ | DPP4 | P27487 | 4/20 | 0.36 |
| ▸ | DPP8 | Q6V1X1 | 4/20 | 0.36 |
| ▸ | DPP9 | Q86TI2 | 4/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | FKBP1A | P62942 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.32 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.32 |
| ▸ | RELA | Q04206 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13920777 | 1.00 | MMP2 (0.52) | MMP2ANPEPDPP7DPP4DPP8 | |
| SCHEMBL15482322 | 0.86 | MMP2 (0.70) | MMP2ANPEPDPP7DPP4DPP8 | |
| SCHEMBL13768839 | 0.86 | MMP2 (0.70) | MMP2ANPEPDPP7DPP4DPP8 | |
| SCHEMBL13494285 | 0.86 | MMP2 (0.70) | MMP2ANPEPDPP7DPP4DPP8 | |
| SCHEMBL13841888 | 0.86 | MMP2 (0.70) | MMP2ANPEPDPP7DPP4DPP8 | |
| SCHEMBL13937654 | 0.86 | MMP2 (0.70) | MMP2ANPEPDPP7DPP4DPP8 | |
| SCHEMBL20215871 | 0.86 | MMP2 (0.70) | MMP2ANPEPDPP7DPP4DPP8 | |
| SCHEMBL23038367 | 0.84 | MMP2 (0.51) | MMP2ANPEPDPP7DPP4DPP8 | |
| SCHEMBL13836866 | 0.84 | MMP2 (0.51) | MMP2ANPEPDPP7DPP4DPP8 | |
| SCHEMBL20705291 | 0.84 | MMP2 (0.51) | MMP2ANPEPDPP7DPP4DPP8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7511062-B2 | Substituted 2-quinolyl-oxazoles useful as PDE4 inhibitors | SCHERING CORPORATION (US) | 2009-03-31 | — | — | US | disclosed |