Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GLP1R | P43220 | 8/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | EPOR | P19235 | 3/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | FAAH | O00519 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | FOLH1 | Q04609 | 2/20 | 0.31 |
| ▸ | CASP2 | P42575 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25898599 | 0.92 | GLP1R (0.50) | GLP1RTSHREPORFOLH1 | |
| SCHEMBL13805654 | 0.90 | GLP1R (0.53) | GLP1RTSHRMEN1KMT2AFAAH | |
| SCHEMBL13805653 | 0.89 | GLP1R (0.57) | GLP1RFAAHCASP2 | |
| SCHEMBL13805652 | 0.89 | GLP1R (0.49) | GLP1RTSHRMEN1KMT2AFAAH | |
| SCHEMBL12118613 | 0.87 | GLP1R (0.42) | GLP1RTSHRMEN1KMT2AFAAH | |
| SCHEMBL15494034 | 0.87 | GLP1R (0.46) | GLP1RTSHRMEN1KMT2AEPOR | |
| SCHEMBL16350406 | 0.87 | GLP1R (0.46) | GLP1RTSHRMEN1KMT2AEPOR | |
| SCHEMBL14683460 | 0.86 | GLP1R (0.41) | GLP1RTSHRMEN1KMT2AHPGD | |
| SCHEMBL71906 | 0.86 | MEN1 (0.45) | GLP1RTSHRMEN1KMT2AFAAH | |
| SCHEMBL71315 | 0.86 | GLP1R (0.46) | GLP1RTSHRMEN1KMT2AFAAH |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7666979-B2 | polyvalent targeting ligands that bind to cells used for diagnosis of diseases sensitivity to angiogenesis factor | BRACCO INTERNATIONAL B.V. (NL) | 2010-02-23 | — | — | US | disclosed |