Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GLP1R | P43220 | 8/20 | 0.57 |
| ▸ | FAAH | O00519 | 5/20 | 0.44 |
| ▸ | CASP2 | P42575 | 1/20 | 0.42 |
| ▸ | NAAA | Q02083 | 1/20 | 0.40 |
| ▸ | DNM1 | Q05193 | 1/20 | 0.40 |
| ▸ | EPHX2 | P34913 | 3/20 | 0.40 |
| ▸ | SLC6A5 | Q9Y345 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13805654 | 0.96 | GLP1R (0.53) | GLP1RFAAHCASP2NAAA | |
| SCHEMBL13805652 | 0.93 | GLP1R (0.49) | GLP1RFAAHCASP2NAAA | |
| SCHEMBL71147 | 0.90 | GLP1R (0.46) | GLP1RFAAHCASP2EPHX2 | |
| SCHEMBL71315 | 0.90 | GLP1R (0.46) | GLP1RFAAHCASP2EPHX2 | |
| SCHEMBL16350545 | 0.89 | GLP1R (0.46) | GLP1RFAAHCASP2 | |
| SCHEMBL25898599 | 0.88 | GLP1R (0.50) | GLP1REPHX2 | |
| SCHEMBL14683527 | 0.88 | GLP1R (0.44) | GLP1RFAAHEPHX2 | |
| SCHEMBL71906 | 0.88 | MEN1 (0.45) | GLP1RFAAHEPHX2 | |
| SCHEMBL14683467 | 0.88 | GLP1R (0.44) | GLP1RFAAHEPHX2 | |
| SCHEMBL14683575 | 0.87 | FAAH (0.43) | GLP1RFAAHCASP2EPHX2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090156478-A1 | Acylated GLP-1 Compounds | NOVO NORDISK A/S (DK) | 2009-06-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090156478-A1 | Acylated GLP-1 Compounds | GLP1R, GIPR, GCGR | GLP1R 1/4885FAAH 193/4885CASP2 578/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.