SCHEMBL16350682

COCCN(CC(=O)N(CCCCN)CC(=O)N(CCOC)CC(=O)N(CCOC)CC(=O)N[C@@H](CCCCNC(=O)CCCCC1SC[C@@H]2NC(=O)N[C@H]12)C(N)=O)C(C)=O

nearest known ligand 0.51

Predicted protein targets (top 11)

	gene	UniProt	supporting neighbours	confidence
▸	FOLH1	Q04609	6/20	0.51

▸	TDP1	Q9NUW8	2/20	0.49

▸	PRSS1	P07477	3/20	0.47

▸	PRSS2	P07478	3/20	0.47

▸	PRSS3	P35030	3/20	0.47

▸	TPSAB1	Q15661	3/20	0.47

▸	PLG	P00747	2/20	0.47

▸	PLCD1	P51178	1/20	0.44

▸	F2	P00734	2/20	0.44

▸	CAPN1	P07384	2/20	0.43

▸	CNR1	P21554	1/20	0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compound	similarity	top predicted	shared targets
SCHEMBL13045421	0.95	TDP1 (0.54)	FOLH1TDP1PRSS1PRSS2PRSS3
SCHEMBL14601079	0.95	TDP1 (0.54)	FOLH1TDP1PRSS1PRSS2PRSS3
SCHEMBL16329968	0.94	TDP1 (0.49)	FOLH1TDP1PRSS1PRSS2PRSS3
SCHEMBL16299318	0.94	TDP1 (0.48)	FOLH1TDP1PRSS1PRSS2PRSS3
SCHEMBL13045429	0.94	TDP1 (0.49)	FOLH1TDP1PRSS1PRSS2PRSS3
SCHEMBL13045392	0.93	FOLH1 (0.43)	FOLH1TDP1PRSS1PRSS2PRSS3
SCHEMBL13045423	0.91	TDP1 (0.47)	FOLH1TDP1PRSS1PRSS2PRSS3
SCHEMBL16350641	0.90	FOLH1 (0.48)	FOLH1TDP1PRSS1PRSS2PRSS3
SCHEMBL16315933	0.89	TDP1 (0.53)	FOLH1TDP1PRSS1PRSS2PRSS3
SCHEMBL16350819	0.89	FOLH1 (0.48)	FOLH1TDP1PRSS1PRSS2PRSS3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

Patent	Title	Assignee	Published	Priority	Filing	Country	Status
US-7834144-B2	Prion-specific peptoid reagents	NOVARTIS AG (CH)	2010-11-16	—	—	US	disclosed