Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.54 |
| ▸ | FOLH1 | Q04609 | 5/20 | 0.51 |
| ▸ | CAPN1 | P07384 | 2/20 | 0.47 |
| ▸ | PRSS1 | P07477 | 2/20 | 0.46 |
| ▸ | PRSS2 | P07478 | 2/20 | 0.46 |
| ▸ | PRSS3 | P35030 | 2/20 | 0.46 |
| ▸ | TPSAB1 | Q15661 | 2/20 | 0.46 |
| ▸ | PLG | P00747 | 1/20 | 0.46 |
| ▸ | CA12 | O43570 | 1/20 | 0.44 |
| ▸ | CA1 | P00915 | 1/20 | 0.44 |
| ▸ | CA2 | P00918 | 1/20 | 0.44 |
| ▸ | CA9 | Q16790 | 1/20 | 0.44 |
| ▸ | ITGB1 | P05556 | 1/20 | 0.43 |
| ▸ | ITGA4 | P13612 | 1/20 | 0.43 |
| ▸ | PLCD1 | P51178 | 1/20 | 0.43 |
| ▸ | CNR1 | P21554 | 2/20 | 0.42 |
| ▸ | F2 | P00734 | 1/20 | 0.42 |
| ▸ | PLCG1 | P19174 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13045421 | 1.00 | TDP1 (0.54) | TDP1FOLH1CAPN1PRSS1PRSS2 | |
| SCHEMBL16350682 | 0.95 | FOLH1 (0.51) | TDP1FOLH1CAPN1PRSS1PRSS2 | |
| SCHEMBL10085160 | 0.92 | TDP1 (0.44) | TDP1FOLH1CAPN1PRSS1PRSS2 | |
| SCHEMBL16350635 | 0.92 | FOLH1 (0.56) | TDP1FOLH1PRSS1PRSS2PRSS3 | |
| SCHEMBL13045436 | 0.91 | FOLH1 (0.48) | TDP1FOLH1CAPN1PRSS1PRSS2 | |
| SCHEMBL13045443 | 0.90 | FOLH1 (0.48) | TDP1FOLH1CAPN1PRSS1PRSS2 | |
| SCHEMBL13045432 | 0.90 | FOLH1 (0.48) | TDP1FOLH1CAPN1PRSS1PRSS2 | |
| SCHEMBL16329968 | 0.90 | TDP1 (0.49) | TDP1FOLH1CAPN1PRSS1PRSS2 | |
| SCHEMBL16299318 | 0.89 | TDP1 (0.48) | TDP1FOLH1CAPN1PRSS1PRSS2 | |
| SCHEMBL13045429 | 0.89 | TDP1 (0.49) | TDP1FOLH1CAPN1PRSS1PRSS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007030804-A1 | PRION-SPECIFIC PEPTOID REAGENTS | NOVARTIS AG (CH) | 2007-03-15 | — | — | WO | disclosed |