SCHEMBL16351204

CCOCC(=O)N[C@H](C(=O)N[C@@H](CCCCN)C(=O)N1CCC[C@H]1C(=O)N1CCC[C@H]1C(=O)N[C@@H](CCCNC(=N)N)C(=O)O)[C@@H](C)O

nearest known ligand 0.46

Predicted protein targets (top 7)

	gene	UniProt	supporting neighbours	confidence
▸	RAMP3	O60896	11/20	0.46

▸	CALCR	P30988	11/20	0.46

▸	IL23R	Q5VWK5	1/20	0.44

▸	GRB2	P62993	1/20	0.44

▸	OPRM1	P35372	6/20	0.44

▸	OPRK1	P41145	6/20	0.44

▸	CAPN1	P07384	1/20	0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compound	similarity	top predicted	shared targets
SCHEMBL12339085	1.00	RAMP3 (0.46)	RAMP3CALCRIL23RGRB2OPRM1
SCHEMBL14452355	0.92	GRB2 (0.45)	RAMP3CALCRGRB2OPRM1OPRK1
SCHEMBL13084700	0.91	RAMP3 (0.47)	RAMP3CALCRIL23RGRB2OPRM1
SCHEMBL13084645	0.91	RAMP3 (0.47)	RAMP3CALCRIL23RGRB2OPRM1
SCHEMBL12314876	0.91	RAMP3 (0.47)	RAMP3CALCRIL23RGRB2OPRM1
SCHEMBL12314880	0.91	RAMP3 (0.47)	RAMP3CALCRIL23RGRB2OPRM1
SCHEMBL16351202	0.90	OPRM1 (0.49)	RAMP3CALCRGRB2OPRM1OPRK1
SCHEMBL16330316	0.89	RAMP3 (0.45)	RAMP3CALCRIL23RGRB2OPRM1
SCHEMBL16340730	0.87	RAMP3 (0.50)	RAMP3CALCRIL23R
SCHEMBL13084631	0.86	GRB2 (0.50)	RAMP3CALCRGRB2OPRM1OPRK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

Patent	Title	Assignee	Published	Priority	Filing	Country	Status
US-8263739-B2	also targeting tumor cells that express vascular endothelial growth factor neuropilin-1 receptor; radiotherapy; radiopharmaceuticals; treating angiogenesis	BRACCO SUISSE SA (CH)	2012-09-11	—	—	US	disclosed