Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ENPP1 | P22413 | 6/20 | 1.00 |
| ▸ | P2RX1 | P51575 | 3/20 | 0.86 |
| ▸ | P2RX3 | P56373 | 3/20 | 0.86 |
| ▸ | TSHR | P16473 | 1/20 | 0.82 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.82 |
| ▸ | LMNA | P02545 | 1/20 | 0.82 |
| ▸ | BLM | P54132 | 1/20 | 0.82 |
| ▸ | PLCG1 | P19174 | 1/20 | 0.81 |
| ▸ | NT5E | P21589 | 1/20 | 0.81 |
| ▸ | P2RY11 | Q96G91 | 2/20 | 0.79 |
| ▸ | P2RY1 | P47900 | 6/20 | 0.78 |
| ▸ | P2RY2 | P41231 | 3/20 | 0.78 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.78 |
| ▸ | SRC | P12931 | 2/20 | 0.78 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.78 |
| ▸ | P2RX4 | Q99571 | 1/20 | 0.78 |
| ▸ | P2RX2 | Q9UBL9 | 1/20 | 0.78 |
| ▸ | TRPM2 | O94759 | 2/20 | 0.75 |
| ▸ | DNPH1 | O43598 | 1/20 | 0.75 |
| ▸ | PRKAB2 | O43741 | 1/20 | 0.75 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21362894 | 1.00 | ENPP1 (1.00) | ENPP1P2RX1P2RX3TSHRKDM4E | |
| SCHEMBL22918310 | 1.00 | ENPP1 (1.00) | ENPP1P2RX1P2RX3TSHRKDM4E | |
| SCHEMBL29941042 | 0.94 | ENPP1 (0.90) | ENPP1P2RX1P2RX3TSHRKDM4E | |
| SCHEMBL16674879 | 0.94 | ENPP1 (0.92) | ENPP1P2RX1P2RX3TSHRKDM4E | |
| SCHEMBL18351578 | 0.94 | ENPP1 (0.92) | ENPP1P2RX1P2RX3TSHRKDM4E | |
| Diphosphomethylphosphonic Acid Adenosyl Ester SCHEMBL2345274 | 0.93 | ENPP1 (1.00) | ENPP1P2RX1P2RX3TSHRKDM4E | |
| Diphosphomethylphosphonic Acid Adenosyl Ester SCHEMBL29428268 | 0.93 | ENPP1 (1.00) | ENPP1P2RX1P2RX3TSHRKDM4E | |
| SCHEMBL21362946 | 0.91 | ENPP1 (0.86) | ENPP1P2RX1P2RX3TSHRKDM4E | |
| Atpgammas SCHEMBL77440 | 0.90 | P2RY1 (0.93) | ENPP1P2RX1P2RX3P2RY11P2RY1 | |
| SCHEMBL16674886 | 0.90 | P2RX1 (0.93) | ENPP1P2RX1P2RX3TSHRKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20140378408-A1 | NUCLEOSIDE 5'-PHOSPHOROTHIOATE ANALOGUES AND USES THEREOF | BAR ILAN UNIVERSITY AN ISRAELI UNIVERSITY (IL) | 2014-12-25 | — | — | US | disclosed |
| US-20140378408-A1 | NUCLEOSIDE 5'-PHOSPHOROTHIOATE ANALOGUES AND USES THEREOF | BAR ILAN UNIVERSITY AN ISRAELI UNIVERSITY (IL) | 2014-12-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140378408-A1 | NUCLEOSIDE 5'-PHOSPHOROTHIOATE ANALOGUES AND USES THEREOF | CCL2, NUDT1, CXCL12 | ENPP1 74/4885P2RX1 111/4885P2RX3 110/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.