Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1B1 | Q16678 | 5/20 | 0.69 |
| ▸ | ABCB1 | P08183 | 4/20 | 0.69 |
| ▸ | CYP1A1 | P04798 | 4/20 | 0.69 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.69 |
| ▸ | MAPT | P10636 | 1/20 | 0.69 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.61 |
| ▸ | CYP3A4 | P08684 | 5/20 | 0.61 |
| ▸ | POLB | P06746 | 1/20 | 0.61 |
| ▸ | HPGD | P15428 | 1/20 | 0.61 |
| ▸ | PDE4D | Q08499 | 2/20 | 0.61 |
| ▸ | BACE1 | P56817 | 4/20 | 0.61 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.56 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.56 |
| ▸ | XPO1 | O14980 | 1/20 | 0.54 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.54 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.54 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.54 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.54 |
| ▸ | KCNA2 | P16389 | 2/20 | 0.48 |
| ▸ | MAOA | P21397 | 2/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29740208 | 1.00 | CYP1B1 (0.69) | CYP1B1ABCB1CYP1A1CYP1A2MAPT | |
| SCHEMBL30945593 | 0.86 | PDE4D (0.55) | CYP1B1ABCB1CYP1A1CYP1A2MAPT | |
| Phellopterin SCHEMBL2468854 | 0.82 | CYP1B1 (1.00) | CYP1B1ABCB1CYP1A1CYP1A2MAPT | |
| SCHEMBL6997006 | 0.81 | CYP3A4 (0.69) | CYP1B1ABCB1CYP1A1CYP1A2MAPT | |
| Kinidilin SCHEMBL28952586 | 0.80 | CYP1B1 (0.91) | CYP1B1ABCB1CYP1A1CYP1A2MAPT | |
| SCHEMBL6272567 | 0.79 | MAOA (0.54) | CYP1B1ABCB1CYP1A1CYP1A2MAPT | |
| SCHEMBL30985284 | 0.78 | KDM4E (0.71) | CYP1B1ABCB1CYP1A1CYP1A2MAPT | |
| Isopimpinellin SCHEMBL498907 | 0.77 | CYP3A4 (1.00) | CYP1B1ABCB1CYP1A1CYP1A2MAPT | |
| Isopimpinellin SCHEMBL29568822 | 0.77 | CYP3A4 (1.00) | CYP1B1ABCB1CYP1A1CYP1A2MAPT | |
| SCHEMBL13532215 | 0.77 | BACE1 (0.57) | CYP1B1ABCB1CYP1A1CYP1A2MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20140377386-A1 | PLANT-BASED INHIBITORS OF KETOHEXOKINASE FOR THE SUPPORT OF WEIGHT MANAGEMENT | ACCESS BUSINESS GROUP INTERNATIONAL LLC (US) | 2014-12-25 | — | — | US | disclosed |
| US-20140377386-A1 | PLANT-BASED INHIBITORS OF KETOHEXOKINASE FOR THE SUPPORT OF WEIGHT MANAGEMENT | ACCESS BUSINESS GROUP INTERNATIONAL LLC (US) | 2014-12-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140377386-A1 | PLANT-BASED INHIBITORS OF KETOHEXOKINASE FOR THE SUPPORT OF WEIGHT MANAGEMENT | KHK, GCK, HK1 | CYP1B1 2686/4885ABCB1 2218/4885CYP1A1 1834/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.