Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FASN | P49327 | 10/20 | 0.59 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.37 |
| ▸ | PLA2G5 | P39877 | 1/20 | 0.37 |
| ▸ | PTGES | O14684 | 3/20 | 0.32 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1785484 | 0.93 | FASN (0.60) | FASNPLA2G2APLA2G5PTGESALOX5 | |
| SCHEMBL19236519 | 0.93 | FASN (0.67) | FASNPTGESALOX5 | |
| SCHEMBL4742082 | 0.86 | FASN (0.63) | FASNPTGESALOX5 | |
| SCHEMBL30212041 | 0.85 | FASN (0.80) | FASNPLA2G2APLA2G5PTGESALOX5 | |
| SCHEMBL155672 | 0.81 | FASN (0.48) | FASN | |
| SCHEMBL30212058 | 0.81 | FASN (0.72) | FASNPLA2G2APLA2G5PTGESALOX5 | |
| SCHEMBL30212093 | 0.79 | FASN (0.80) | FASNPLA2G2APLA2G5PTGESALOX5 | |
| SCHEMBL29466102 | 0.78 | FASN (0.91) | FASNPTGESALOX5 | |
| SCHEMBL28043703 | 0.77 | FASN (0.89) | FASNPTGESALOX5 | |
| SCHEMBL8571259 | 0.75 | FASN (0.51) | FASNPLA2G2APLA2G5PTGESALOX5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20140377386-A1 | PLANT-BASED INHIBITORS OF KETOHEXOKINASE FOR THE SUPPORT OF WEIGHT MANAGEMENT | ACCESS BUSINESS GROUP INTERNATIONAL LLC (US) | 2014-12-25 | — | — | US | disclosed |
| US-20140377386-A1 | PLANT-BASED INHIBITORS OF KETOHEXOKINASE FOR THE SUPPORT OF WEIGHT MANAGEMENT | ACCESS BUSINESS GROUP INTERNATIONAL LLC (US) | 2014-12-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140377386-A1 | PLANT-BASED INHIBITORS OF KETOHEXOKINASE FOR THE SUPPORT OF WEIGHT MANAGEMENT | KHK, GCK, HK1 | FASN 397/4885PLA2G2A 4748/4885PLA2G5 4504/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.