SCHEMBL1785484

SCHEMBL1785484

CCCC(=O)C1=C(O)C(C)(C)C(O)=C(Cc2c(O)c(C)c(O)c(C(=O)CCC)c2O)C1=O

nearest known ligand 0.60

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
▸ FASN P49327 10/20 0.60
▸ PLA2G2A P14555 1/20 0.39
▸ PLA2G5 P39877 1/20 0.39
▸ PTGES O14684 2/20 0.32
▸ ALOX5 P09917 2/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16352047 0.93 FASN (0.59) FASNPLA2G2APLA2G5PTGESALOX5
SCHEMBL4742082 0.93 FASN (0.63) FASNPTGESALOX5
SCHEMBL155672 0.88 FASN (0.48) FASN
SCHEMBL30212058 0.87 FASN (0.72) FASNPLA2G2APLA2G5PTGESALOX5
SCHEMBL19236519 0.85 FASN (0.67) FASNPTGESALOX5
SCHEMBL30212041 0.83 FASN (0.80) FASNPLA2G2APLA2G5PTGESALOX5
SCHEMBL30212093 0.83 FASN (0.80) FASNPLA2G2APLA2G5PTGESALOX5
SCHEMBL4962391 0.82 FASN (0.64) FASN
SCHEMBL8571259 0.81 FASN (0.51) FASNPLA2G2APLA2G5PTGESALOX5
Desaspidin SCHEMBL29613713 0.78 FASN (0.51) FASNPLA2G2APLA2G5PTGESALOX5

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 129 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-109852226-A A kind of highway crash wall coating and its preparation process 山西大学 2019-06-07 — — CN claimed
CN-109662951-A A kind of dispersion tablet of vasilowy hydrochlaride and its preparation process of high bioavilability 辰欣药业股份有限公司 2019-04-23 — — CN claimed
CN-108997099-A A kind of fully synthetic new method of natural products flavaspidic acid BB 中国药科大学 2018-12-14 — — CN claimed
CN-108624097-A A kind of luminous exterior wall coating 侯娟 2018-10-09 — — CN claimed
CN-108003724-A A kind of energy-accumulating luminous paint for highway anticollision wall and preparation method thereof 山西省交通科学研究院 2018-05-08 — — CN claimed
CN-107987673-A A kind of pipeline anti-corrosive paint and preparation method thereof 山西省交通科学研究院 2018-05-04 — — CN claimed
CN-107916086-A A kind of toughening type aqueous epoxy resin systems and preparation method thereof 山西省交通科学研究院 2018-04-17 — — CN claimed
CN-107913262-A Flavaspidic acid AB resisiting influenza virus functions 中国医学科学院药用植物研究所 2018-04-17 — — CN claimed
CN-107837247-A Dryopteris fragrans phloroglucinol compound flavaspidic acid BB and its antibacterial applications 广东药科大学 2018-03-27 — — CN claimed
CN-105555287-A Plant-based ketohexokinase inhibitors for supporting weight management ACCESS BUSINESS GROUP INT LLC 2016-05-04 — — CN claimed
EP-3010520-A1 PLANT-BASED INHIBITORS OF KETOHEXOKINASE FOR THE SUPPORT OF WEIGHT MANAGEMENT Access Business Group International LLC (US) 2016-04-27 — — EP claimed
CN-105362485-A smearing preparation for treating animal skin diseases and its preparation method and application FAN ERGEN 2016-03-02 — — CN claimed
US-20140377386-A1 PLANT-BASED INHIBITORS OF KETOHEXOKINASE FOR THE SUPPORT OF WEIGHT MANAGEMENT ACCESS BUSINESS GROUP INTERNATIONAL LLC (US) 2014-12-25 — — US claimed
WO-2014204853-A1 PLANT-BASED INHIBITORS OF KETOHEXOKINASE FOR THE SUPPORT OF WEIGHT MANAGEMENT ACCESS BUSINESS GROUP INTERNATIONAL LLC (US) 2014-12-24 — — WO claimed
CN-102379863-A Application of flavaspidic acid AB to preparation of antitumor and antivirus medicament INST MEDICINAL PLANT DEV CAMS 2012-03-21 — — CN claimed
CN-100556415-C The medicine of a kind of influenza and bird flu virus UNIV SOUTH CHINA AGRICULT (CN) 2009-11-04 — — CN claimed
CN-1846717-A Medicine for treating influenza and bird flu UNIV SOUTH CHINA AGRICULT (CN) 2006-10-18 — — CN claimed
CN-1475271-A Application of cytomium fortunei effectire part and monomer in medicament for anticanner and anti arthritis 北京扬新科技有限公司 2004-02-18 — — CN claimed
US-12178790-B2 Antibacterial compound isolated from Psiloxylon mauritianum and its derivatives SORRES, Jonathan (FR) 2024-12-31 — — US disclosed
WO-1991002040-A1 CYCLODEXTRIN LABELS FOR NUCLEIC ACID AND BIOCHEMICAL ANALYSIS KOSAK KENNETH M (US) 1991-02-21 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20140377386-A1 PLANT-BASED INHIBITORS OF KETOHEXOKINASE FOR THE SUPPORT OF WEIGHT MANAGEMENT KHK, GCK, HK1 FASN 397/4885PLA2G2A 4748/4885PLA2G5 4504/4885
US-12178790-B2 Antibacterial compound isolated from Psiloxylon mauritianum and its derivatives AAAS, PNN, MRPL9 FASN 27/4885PLA2G2A 3357/4885PLA2G5 1955/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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