Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC34A2 | O95436 | 1/20 | 0.72 |
| ▸ | ROCK2 | O75116 | 2/20 | 0.39 |
| ▸ | ROCK1 | Q13464 | 2/20 | 0.39 |
| ▸ | GPR52 | Q9Y2T5 | 4/20 | 0.38 |
| ▸ | PSEN1 | P49768 | 1/20 | 0.37 |
| ▸ | PSEN2 | P49810 | 1/20 | 0.37 |
| ▸ | APH1B | Q8WW43 | 1/20 | 0.37 |
| ▸ | NCSTN | Q92542 | 1/20 | 0.37 |
| ▸ | APH1A | Q96BI3 | 1/20 | 0.37 |
| ▸ | PSENEN | Q9NZ42 | 1/20 | 0.37 |
| ▸ | SCD | O00767 | 1/20 | 0.36 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.36 |
| ▸ | MLYCD | O95822 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6001829 | 0.94 | SLC34A2 (0.82) | SLC34A2ROCK2ROCK1GPR52PSEN1 | |
| SCHEMBL47055 | 0.94 | SLC34A2 (0.82) | SLC34A2ROCK2ROCK1GPR52PSEN1 | |
| SCHEMBL46770 | 0.94 | SLC34A2 (0.82) | SLC34A2ROCK2ROCK1GPR52PSEN1 | |
| SCHEMBL44914 | 0.94 | SLC34A2 (0.82) | SLC34A2ROCK2ROCK1GPR52PSEN1 | |
| SCHEMBL18482743 | 0.93 | SLC34A2 (0.73) | SLC34A2ROCK2ROCK1GPR52PSEN1 | |
| SCHEMBL16355245 | 0.93 | SLC34A2 (0.73) | SLC34A2ROCK2ROCK1GPR52PSEN1 | |
| SCHEMBL6001902 | 0.93 | SLC34A2 (0.73) | SLC34A2ROCK2ROCK1GPR52PSEN1 | |
| SCHEMBL6003159 | 0.93 | SLC34A2 (0.69) | SLC34A2ROCK2ROCK1GPR52PSEN1 | |
| SCHEMBL15432885 | 0.93 | SLC34A2 (0.69) | SLC34A2ROCK2ROCK1GPR52PSEN1 | |
| SCHEMBL10290323 | 0.93 | SLC34A2 (0.69) | SLC34A2ROCK2ROCK1GPR52PSEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8916569-B2 | Compounds and methods for inhibiting phosphate transport | ARDELYX, INC. (US) | 2014-12-23 | — | — | US | disclosed |
| US-8916569-B2 | Compounds and methods for inhibiting phosphate transport | ARDELYX, INC. (US) | 2014-12-23 | — | — | US | disclosed |