Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC34A2 | O95436 | 1/20 | 0.73 |
| ▸ | ROCK2 | O75116 | 3/20 | 0.41 |
| ▸ | ROCK1 | Q13464 | 2/20 | 0.41 |
| ▸ | PSEN1 | P49768 | 1/20 | 0.39 |
| ▸ | PSEN2 | P49810 | 1/20 | 0.39 |
| ▸ | APH1B | Q8WW43 | 1/20 | 0.39 |
| ▸ | NCSTN | Q92542 | 1/20 | 0.39 |
| ▸ | APH1A | Q96BI3 | 1/20 | 0.39 |
| ▸ | PSENEN | Q9NZ42 | 1/20 | 0.39 |
| ▸ | GPR52 | Q9Y2T5 | 3/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | MLYCD | O95822 | 1/20 | 0.36 |
| ▸ | KDM1A | O60341 | 2/20 | 0.36 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6001902 | 0.95 | SLC34A2 (0.73) | SLC34A2ROCK2ROCK1PSEN1PSEN2 | |
| SCHEMBL46547 | 0.94 | SLC34A2 (0.71) | SLC34A2ROCK2ROCK1PSEN1PSEN2 | |
| SCHEMBL2721831 | 0.94 | SLC34A2 (0.71) | SLC34A2ROCK2ROCK1PSEN1PSEN2 | |
| SCHEMBL47055 | 0.94 | SLC34A2 (0.82) | SLC34A2ROCK2ROCK1PSEN1PSEN2 | |
| SCHEMBL46770 | 0.94 | SLC34A2 (0.82) | SLC34A2ROCK2ROCK1PSEN1PSEN2 | |
| SCHEMBL44914 | 0.94 | SLC34A2 (0.82) | SLC34A2ROCK2ROCK1PSEN1PSEN2 | |
| SCHEMBL6001829 | 0.94 | SLC34A2 (0.82) | SLC34A2ROCK2ROCK1PSEN1PSEN2 | |
| SCHEMBL16355245 | 0.93 | SLC34A2 (0.73) | SLC34A2ROCK2ROCK1PSEN1PSEN2 | |
| SCHEMBL16355244 | 0.93 | SLC34A2 (0.72) | SLC34A2ROCK2ROCK1PSEN1PSEN2 | |
| SCHEMBL15432880 | 0.93 | SLC34A2 (0.72) | SLC34A2ROCK2ROCK1PSEN1PSEN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170037010-A1 | COMPOUNDS AND METHODS FOR INHIBITING PHOSPHATE TRANSPORT | ARDELYX, INC. | 2017-02-09 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170037010-A1 | COMPOUNDS AND METHODS FOR INHIBITING PHOSPHATE TRANSPORT | SLC34A2, SLC34A1, SLC10A2 | SLC34A2 1/4885ROCK2 2489/4885ROCK1 1903/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.