SCHEMBL16355266

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL15158447	0.90	ALDH1A1 (0.47)	CYP2A6SMN1; SMN2KDM4EALDH1A1MAPT
	SCHEMBL15158443	0.89	ALDH1A1 (0.46)	CYP2A6SMN1; SMN2KDM4EALDH1A1MAPT
	SCHEMBL14463294	0.89	ALDH1A1 (0.46)	CYP2A6SMN1; SMN2KDM4EALDH1A1MAPT
	SCHEMBL15158412	0.89	KDM4E (0.42)	SMN1; SMN2KDM4EALDH1A1MAPTHPGD
	SCHEMBL15158448	0.89	ALDH1A1 (0.46)	CYP2A6SMN1; SMN2KDM4EALDH1A1MAPT
	SCHEMBL15158403	0.88	MAPK1 (0.43)	SMN1; SMN2KDM4EALDH1A1MAPTHPGD
	SCHEMBL16355273	0.86	DHODH (0.40)	SMN1; SMN2KDM4EALDH1A1MAPTHPGD
	SCHEMBL15237198	0.86	MAPT (0.40)	SMN1; SMN2KDM4EALDH1A1MAPTHPGD
	SCHEMBL17320751	0.86	CYP2A6 (0.49)	CYP2A6SMN1; SMN2KDM4EALDH1A1MAPT
	SCHEMBL15237199	0.86	KDM4E (0.44)	SMN1; SMN2KDM4EALDH1A1MAPTHPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.