Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADAM17 | P78536 | 6/20 | 0.45 |
| ▸ | CHRM4 | P08173 | 6/20 | 0.42 |
| ▸ | LDHA | P00338 | 1/20 | 0.39 |
| ▸ | NAMPT | P43490 | 3/20 | 0.37 |
| ▸ | GPR6 | P46095 | 3/20 | 0.35 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.34 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8214415 | 0.94 | ADAM17 (0.46) | ADAM17CHRM4LDHANAMPTGPR6 | |
| SCHEMBL8222661 | 0.86 | ADAM17 (0.53) | ADAM17CHRM4SCN5ASCN9A | |
| SCHEMBL8214329 | 0.84 | ADAM17 (0.44) | ADAM17CHRM4 | |
| SCHEMBL8275981 | 0.83 | NAMPT (0.42) | ADAM17NAMPT | |
| SCHEMBL8221438 | 0.82 | ADAM17 (0.53) | ADAM17CHRM4SCN5ASCN9A | |
| SCHEMBL8221453 | 0.82 | ADAM17 (0.53) | ADAM17CHRM4SCN5ASCN9A | |
| SCHEMBL8273348 | 0.82 | ADAM17 (0.53) | ADAM17CHRM4SCN5ASCN9A | |
| SCHEMBL8214539 | 0.82 | ADAM17 (0.45) | ADAM17CHRM4NAMPT | |
| SCHEMBL8221817 | 0.81 | ADAM17 (0.43) | ADAM17CHRM4GPR6 | |
| SCHEMBL8213698 | 0.81 | ADAM17 (0.53) | ADAM17CHRM4SCN5ASCN9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007064749-A1 | COMPOUNDS FOR THE TREATMENT OF INFLAMMATORY DISORDERS AND MICROBIAL DISEASES | SCHERING CORPORATION (US) | 2007-06-07 | — | — | WO | disclosed |