Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATM | Q13315 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.39 |
| ▸ | TSHR | P16473 | 2/20 | 0.39 |
| ▸ | USP2 | O75604 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | LGALS8 | O00214 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1104570 | 1.00 | ATM (0.39) | ATMALDH1A1TSHRUSP2MAPT | |
| SCHEMBL1104567 | 0.90 | ATM (0.40) | ATMALDH1A1TSHRUSP2MAPT | |
| SCHEMBL13743882 | 0.86 | ALDH1A1 (0.39) | ATMALDH1A1TSHRUSP2MAPT | |
| SCHEMBL10188814 | 0.85 | CYP3A4 (0.39) | ATMALDH1A1TSHRUSP2MAPT | |
| SCHEMBL13325754 | 0.82 | ATM (0.39) | ATMALDH1A1TSHRUSP2MAPT | |
| SCHEMBL1104566 | 0.82 | ATM (0.48) | ATMALDH1A1TSHRMAPTL3MBTL1 | |
| SCHEMBL18356894 | 0.80 | MAPT (0.36) | ALDH1A1MAPTGAAPOLBTDP1 | |
| SCHEMBL20371029 | 0.79 | ALDH1A1 (0.41) | ATMALDH1A1TSHRUSP2MAPT | |
| SCHEMBL20380432 | 0.79 | ALDH1A1 (0.41) | ATMALDH1A1TSHRUSP2MAPT | |
| SCHEMBL14827501 | 0.77 | ALDH1A1 (0.39) | ATMALDH1A1TSHRUSP2MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2013033230-A1 | OLIGOMER-CONJUGATE COMPLEXES AND THEIR USE | ISIS PHARMACEUTICALS, INC. (US) | 2013-03-07 | — | — | WO | disclosed |