Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RARB | P10826 | 8/20 | 0.37 |
| ▸ | PTH1R | Q03431 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | RARA | P10276 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | MTOR | P42345 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | KDM5A | P29375 | 2/20 | 0.30 |
| ▸ | KDM5B | Q9UGL1 | 2/20 | 0.30 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.30 |
| ▸ | RXRA | P19793 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16358739 | 0.89 | PTH1R (0.33) | RARBPTH1R | |
| SCHEMBL850087 | 0.82 | PTH1R (0.49) | RARBPTH1R | |
| SCHEMBL16358745 | 0.80 | RARB (0.32) | RARB | |
| SCHEMBL879883 | 0.80 | RARB (0.32) | RARB | |
| SCHEMBL17215267 | 0.77 | PTH1R (0.47) | PTH1R | |
| SCHEMBL16358587 | 0.77 | PTH1R (0.47) | PTH1R | |
| SCHEMBL16104848 | 0.77 | PTH1R (0.47) | PTH1R | |
| SCHEMBL847997 | 0.73 | PTH1R (0.49) | PTH1RKMT2A | |
| SCHEMBL848743 | 0.73 | PTH1R (0.49) | PTH1RALDH1A1 | |
| SCHEMBL851046 | 0.72 | PTH1R (0.49) | RARBPTH1R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010126030-A1 | SPIROIMIDAZOLONE DERIVATIVE | 中外製薬株式会社 (JP) | 2010-11-04 | — | — | WO | disclosed |