Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTH1R | Q03431 | 6/20 | 0.36 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL849215 | 1.00 | PTH1R (0.36) | PTH1RPIK3CGTSHRMAPK1PDK2 | |
| SCHEMBL849213 | 1.00 | PTH1R (0.36) | PTH1RPIK3CGTSHRMAPK1PDK2 | |
| SCHEMBL849214 | 1.00 | PTH1R (0.36) | PTH1RPIK3CGTSHRMAPK1PDK2 | |
| SCHEMBL849216 | 1.00 | PTH1R (0.36) | PTH1RPIK3CGTSHRMAPK1PDK2 | |
| SCHEMBL880096 | 0.92 | PTH1R (0.38) | PTH1R | |
| SCHEMBL849703 | 0.87 | PTH1R (0.48) | PTH1RTSHRMAPK1PDK2 | |
| SCHEMBL849702 | 0.87 | PTH1R (0.48) | PTH1RTSHRMAPK1PDK2 | |
| SCHEMBL849704 | 0.87 | PTH1R (0.48) | PTH1RTSHRMAPK1PDK2 | |
| SCHEMBL13554020 | 0.87 | PTH1R (0.37) | PTH1R | |
| SCHEMBL13554021 | 0.85 | PTH1R (0.52) | PTH1R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010126030-A1 | SPIROIMIDAZOLONE DERIVATIVE | 中外製薬株式会社 (JP) | 2010-11-04 | — | — | WO | disclosed |