Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTH1R | Q03431 | 6/20 | 0.38 |
| ▸ | MMP1 | P03956 | 1/20 | 0.31 |
| ▸ | MMP2 | P08253 | 1/20 | 0.31 |
| ▸ | MMP3 | P08254 | 1/20 | 0.31 |
| ▸ | MMP9 | P14780 | 1/20 | 0.31 |
| ▸ | MMP14 | P50281 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL849216 | 0.92 | PTH1R (0.36) | PTH1R | |
| SCHEMBL849214 | 0.92 | PTH1R (0.36) | PTH1R | |
| SCHEMBL16358652 | 0.92 | PTH1R (0.36) | PTH1R | |
| SCHEMBL849215 | 0.92 | PTH1R (0.36) | PTH1R | |
| SCHEMBL849213 | 0.92 | PTH1R (0.36) | PTH1R | |
| SCHEMBL13554020 | 0.90 | PTH1R (0.37) | PTH1R | |
| SCHEMBL13554021 | 0.89 | PTH1R (0.52) | PTH1R | |
| SCHEMBL850208 | 0.88 | PTH1R (0.36) | PTH1R | |
| SCHEMBL850209 | 0.88 | PTH1R (0.36) | PTH1R | |
| SCHEMBL850493 | 0.86 | PTH1R (0.36) | PTH1RMMP2MMP3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2433940-A1 | SPIROIMIDAZOLONE DERIVATIVE | Chugai Seiyaku Kabushiki Kaisha (JP) | 2012-03-28 | — | — | EP | disclosed |