SCHEMBL16358669

SCHEMBL16358669

Cc1cc(CC(C)(C)C)ccc1CCS(=O)(=O)N1CCC2(CC1)N=C(c1cc(O)cc(C(F)(F)F)c1)N(C(=O)OC(C)(C)C)C2=O

nearest known ligand 0.36

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
PTH1R Q03431 7/20 0.36
TACR1 P25103 2/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL850524 0.90 PTH1R (0.37) PTH1RTACR1
SCHEMBL848468 0.85 PTH1R (0.37) PTH1RTACR1
SCHEMBL16358633 0.82 PTH1R (0.38) PTH1RTACR1
SCHEMBL16302620 0.82 PTH1R (0.38) PTH1RTACR1
SCHEMBL851594 0.82 PTH1R (0.35) PTH1RTACR1
SCHEMBL16302629 0.81 PTH1R (0.37) PTH1RTACR1
SCHEMBL851265 0.79 PTH1R (0.35) PTH1R
SCHEMBL851141 0.76 PTH1R (0.47) PTH1RTACR1
SCHEMBL848683 0.76 PTH1R (0.36) PTH1R
SCHEMBL13554454 0.76 PTH1R (0.35) PTH1R

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2010126030-A1 SPIROIMIDAZOLONE DERIVATIVE 中外製薬株式会社 (JP) 2010-11-04 WO disclosed