Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC1 | Q13547 | 1/20 | 0.37 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.37 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.37 |
| ▸ | PTH1R | Q03431 | 5/20 | 0.33 |
| ▸ | AR | P10275 | 1/20 | 0.31 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.30 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.30 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL847572 | 0.86 | PTH1R (0.38) | HDAC1HDAC8HDAC6PTH1R | |
| SCHEMBL847571 | 0.86 | PTH1R (0.38) | HDAC1HDAC8HDAC6PTH1R | |
| SCHEMBL847726 | 0.86 | PTH1R (0.38) | HDAC1HDAC8HDAC6PTH1R | |
| SCHEMBL847573 | 0.86 | PTH1R (0.38) | HDAC1HDAC8HDAC6PTH1R | |
| SCHEMBL847725 | 0.86 | PTH1R (0.38) | HDAC1HDAC8HDAC6PTH1R | |
| SCHEMBL16358330 | 0.85 | HDAC1 (0.39) | HDAC1HDAC8HDAC6PTH1RAR | |
| SCHEMBL847427 | 0.79 | PTH1R (0.47) | HDAC1HDAC8HDAC6PTH1R | |
| SCHEMBL847428 | 0.79 | PTH1R (0.47) | HDAC1HDAC8HDAC6PTH1R | |
| SCHEMBL847504 | 0.79 | PTH1R (0.47) | HDAC1HDAC8HDAC6PTH1R | |
| SCHEMBL16358983 | 0.77 | PTH1R (0.48) | PTH1RAR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010126030-A1 | SPIROIMIDAZOLONE DERIVATIVE | 中外製薬株式会社 (JP) | 2010-11-04 | — | — | WO | disclosed |