SCHEMBL16358983

SCHEMBL16358983

Cc1cc(N2C(=O)CNC2=O)cc(C)c1/C=C/[S+]([O-])N1CCC2(CC1)N=C(c1ccc(F)c(C(F)(F)F)c1)NC2=O

nearest known ligand 0.48

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
PTH1R Q03431 7/20 0.48
AR P10275 6/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL847595 0.86 PTH1R (0.54) PTH1RAR
SCHEMBL847596 0.86 PTH1R (0.54) PTH1RAR
SCHEMBL16359028 0.85 PTH1R (0.35) PTH1RAR
SCHEMBL16302457 0.81 PTH1R (0.33) PTH1RAR
SCHEMBL16302310 0.79 PTH1R (0.34) PTH1R
SCHEMBL16302445 0.79 PTH1R (0.34) PTH1RAR
SCHEMBL850361 0.79 PTH1R (0.75) PTH1RAR
SCHEMBL16358986 0.77 AR (0.36) PTH1RAR
SCHEMBL16358797 0.77 HDAC1 (0.37) PTH1RAR
SCHEMBL16359031 0.76

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2010126030-A1 SPIROIMIDAZOLONE DERIVATIVE 中外製薬株式会社 (JP) 2010-11-04 WO disclosed