SCHEMBL16358982

SCHEMBL16358982

CCCCc1cc(/C=C/c2ccc(N(c3ccccc3)c3ccc4c(c3)c3ccccc3n4-c3ccccc3)cc2)cc(CCCC)c1

nearest known ligand 0.37

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 3/20 0.37
ATM Q13315 2/20 0.37
L3MBTL1 Q9Y468 2/20 0.37
APP P05067 1/20 0.34
ALDH1A1 P00352 2/20 0.33
AKR1C4 P17516 1/20 0.33
AKR1C3 P42330 1/20 0.33
AKR1C2 P52895 1/20 0.33
AKR1C1 Q04828 1/20 0.33
CYP1A2 P05177 1/20 0.33
GLA P06280 1/20 0.33
CYP3A4 P08684 1/20 0.33
CYP2C9 P11712 1/20 0.33
HPGD P15428 1/20 0.33
CYP2C19 P33261 1/20 0.33
CNR2 P34972 2/20 0.32
POLB P06746 1/20 0.32
PKM P14618 1/20 0.32
HTT P42858 1/20 0.32
NPY5R Q15761 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16270550 0.95 AKR1C4 (0.35) KDM4EATML3MBTL1APPALDH1A1
SCHEMBL10123645 0.94 KDM4E (0.38) KDM4EATML3MBTL1APPALDH1A1
SCHEMBL16358944 0.94 KDM4E (0.37) KDM4EATML3MBTL1APPALDH1A1
SCHEMBL10123708 0.89 PLA2G4A (0.38) KDM4EATML3MBTL1APPALDH1A1
SCHEMBL16270539 0.89 AKR1C4 (0.39) KDM4EATML3MBTL1APPALDH1A1
SCHEMBL10123637 0.89 PLA2G4A (0.38) KDM4EAPPALDH1A1CYP1A2GLA
SCHEMBL16358943 0.86 KDM4E (0.40) KDM4EATML3MBTL1APPALDH1A1
SCHEMBL31268435 0.86 KDM4E (0.50) KDM4EATML3MBTL1APPALDH1A1
SCHEMBL36257 0.86 KDM4E (0.50) KDM4EATML3MBTL1APPALDH1A1
SCHEMBL3033494 0.86 KDM4E (0.50) KDM4EATML3MBTL1APPALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2007043371-A1 STILBENE DERIVATIVES, LIGHT-EMITTING ELEMENT AND LIGHT-EMITTING DEVICE SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2007-04-19 WO disclosed