Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRD1 | P41143 | 20/20 | 0.51 |
| ▸ | KCNH2 | Q12809 | 18/20 | 0.51 |
| ▸ | OPRK1 | P41145 | 6/20 | 0.51 |
| ▸ | MRGPRX2 | Q96LB1 | 1/20 | 0.49 |
| ▸ | CYP2D6 | P10635 | 13/20 | 0.48 |
| ▸ | OPRM1 | P35372 | 3/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10258789 | 0.78 | OPRD1 (0.78) | OPRD1KCNH2OPRK1MRGPRX2CYP2D6 | |
| SCHEMBL471573 | 0.77 | OPRD1 (0.49) | OPRD1KCNH2OPRK1MRGPRX2CYP2D6 | |
| SCHEMBL471699 | 0.73 | OPRD1 (0.48) | OPRD1KCNH2OPRK1MRGPRX2CYP2D6 | |
| SCHEMBL16315360 | 0.72 | OPRD1 (0.50) | OPRD1KCNH2OPRK1MRGPRX2CYP2D6 | |
| SCHEMBL471284 | 0.72 | OPRD1 (0.50) | OPRD1KCNH2OPRK1MRGPRX2CYP2D6 | |
| SCHEMBL471288 | 0.71 | OPRD1 (0.72) | OPRD1KCNH2OPRK1MRGPRX2CYP2D6 | |
| SCHEMBL467355 | 0.70 | OPRD1 (0.72) | OPRD1KCNH2OPRK1MRGPRX2CYP2D6 | |
| SCHEMBL16315226 | 0.69 | OPRD1 (0.52) | OPRD1KCNH2OPRK1MRGPRX2CYP2D6 | |
| SCHEMBL12030722 | 0.68 | OPRD1 (0.73) | OPRD1KCNH2OPRK1MRGPRX2CYP2D6 | |
| SCHEMBL16315381 | 0.68 | OPRD1 (0.68) | OPRD1KCNH2OPRK1MRGPRX2CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008033299-A2 | USE OF N-CONTAINING SPIROCOMPOUNDS FOR THE ENHANCEMENT OF COGNITIVE FUNCTION | ADOLOR CORPORATION (US) | 2008-03-20 | — | — | WO | disclosed |