Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.39 |
| ▸ | MEN1 | O00255 | 3/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 5/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | RECQL | P46063 | 1/20 | 0.38 |
| ▸ | PTH1R | Q03431 | 3/20 | 0.37 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16087530 | 0.90 | PTH1R (0.39) | KMT2AMEN1ALDH1A1MAPTTSHR | |
| SCHEMBL849009 | 0.87 | MAPT (0.40) | KMT2AMEN1ALDH1A1MAPTTSHR | |
| SCHEMBL16087592 | 0.86 | PTH1R (0.42) | KMT2AMEN1ALDH1A1MAPTTSHR | |
| SCHEMBL16087562 | 0.84 | MEN1 (0.39) | KMT2AMEN1ALDH1A1MAPTTSHR | |
| SCHEMBL847907 | 0.83 | KMT2A (0.48) | KMT2AMEN1ALDH1A1MAPTTSHR | |
| SCHEMBL849648 | 0.83 | MEN1 (0.41) | KMT2AMEN1ALDH1A1MAPTTSHR | |
| SCHEMBL16087546 | 0.82 | MEN1 (0.39) | KMT2AMEN1ALDH1A1MAPTTSHR | |
| SCHEMBL848776 | 0.82 | MEN1 (0.51) | KMT2AMEN1ALDH1A1MAPTPTH1R | |
| SCHEMBL847373 | 0.82 | MAPT (0.44) | KMT2AMEN1ALDH1A1MAPTTSHR | |
| SCHEMBL13552166 | 0.82 | MEN1 (0.42) | KMT2AMEN1ALDH1A1MAPTTSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010126030-A1 | SPIROIMIDAZOLONE DERIVATIVE | 中外製薬株式会社 (JP) | 2010-11-04 | — | — | WO | disclosed |