SCHEMBL849648

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL848383	0.86	MEN1 (0.41)	MEN1KMT2AALDH1A1PTH1RMAPT
	SCHEMBL847907	0.84	KMT2A (0.48)	MEN1KMT2AALDH1A1MAPTTSHR
	SCHEMBL848776	0.83	MEN1 (0.51)	MEN1KMT2AALDH1A1PTH1RMAPT
	SCHEMBL13552166	0.83	MEN1 (0.42)	MEN1KMT2AALDH1A1PTH1RMAPT
	SCHEMBL849234	0.83	KMT2A (0.43)	MEN1KMT2AALDH1A1PTH1RMAPT
	SCHEMBL849574	0.83	STS (0.46)	MEN1KMT2AALDH1A1PTH1RMAPT
	SCHEMBL848801	0.83	PTH1R (0.42)	MEN1KMT2AALDH1A1PTH1RMAPT
	SCHEMBL16359079	0.83	KMT2A (0.39)	MEN1KMT2AALDH1A1PTH1RMAPT
	SCHEMBL847346	0.82	KMT2A (0.43)	MEN1KMT2AALDH1A1PTH1RMAPT
	SCHEMBL849916	0.81	KMT2A (0.42)	MEN1KMT2AALDH1A1PTH1RMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.