Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRD1 | P41143 | 20/20 | 0.75 |
| ▸ | KCNH2 | Q12809 | 19/20 | 0.75 |
| ▸ | CYP2D6 | P10635 | 17/20 | 0.75 |
| ▸ | OPRM1 | P35372 | 3/20 | 0.66 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.61 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10258603 | 0.94 | OPRD1 (0.80) | OPRD1KCNH2CYP2D6OPRM1OPRK1 | |
| SCHEMBL471585 | 0.85 | OPRD1 (1.00) | OPRD1KCNH2CYP2D6OPRM1OPRK1 | |
| SCHEMBL467302 | 0.81 | OPRD1 (1.00) | OPRD1KCNH2CYP2D6OPRM1OPRK1 | |
| SCHEMBL10258888 | 0.81 | OPRD1 (1.00) | OPRD1KCNH2CYP2D6OPRM1OPRK1 | |
| SCHEMBL471337 | 0.81 | OPRD1 (1.00) | OPRD1KCNH2CYP2D6OPRM1OPRK1 | |
| Hydrochloric Acid SCHEMBL2071898 | 0.80 | OPRD1 (0.98) | OPRD1KCNH2CYP2D6OPRM1OPRK1 | |
| SCHEMBL471580 | 0.80 | OPRD1 (1.00) | OPRD1KCNH2CYP2D6OPRM1OPRK1 | |
| SCHEMBL471405 | 0.79 | OPRD1 (1.00) | OPRD1KCNH2CYP2D6OPRM1OPRK1 | |
| SCHEMBL467434 | 0.79 | OPRD1 (1.00) | OPRD1KCNH2CYP2D6OPRM1OPRK1 | |
| SCHEMBL471407 | 0.79 | OPRD1 (1.00) | OPRD1KCNH2CYP2D6OPRM1OPRK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008033299-A2 | USE OF N-CONTAINING SPIROCOMPOUNDS FOR THE ENHANCEMENT OF COGNITIVE FUNCTION | ADOLOR CORPORATION (US) | 2008-03-20 | — | — | WO | disclosed |