Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPY4R | P50391 | 10/20 | 0.52 |
| ▸ | NPY5R | Q15761 | 6/20 | 0.52 |
| ▸ | NPY1R | P25929 | 5/20 | 0.52 |
| ▸ | NPY2R | P49146 | 3/20 | 0.52 |
| ▸ | TLR2 | O60603 | 1/20 | 0.44 |
| ▸ | ALB | P02768 | 1/20 | 0.43 |
| ▸ | NOD1 | Q9Y239 | 2/20 | 0.41 |
| ▸ | ROCK2 | O75116 | 2/20 | 0.41 |
| ▸ | PRKACA | P17612 | 1/20 | 0.41 |
| ▸ | AKT3 | Q9Y243 | 1/20 | 0.41 |
| ▸ | FNTA | P49354 | 1/20 | 0.39 |
| ▸ | FNTB | P49356 | 1/20 | 0.39 |
| ▸ | PGGT1B | P53609 | 1/20 | 0.39 |
| ▸ | SIRT5 | Q9NXA8 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19346862 | 0.92 | NPY4R (0.48) | NPY4RNPY5RNPY1RNPY2RTLR2 | |
| SCHEMBL9666237 | 0.91 | NOD1 (0.52) | NPY4RNPY5RNPY1RNPY2RTLR2 | |
| SCHEMBL24724855 | 0.91 | TLR2 (0.53) | NPY4RNPY5RNPY1RNPY2RTLR2 | |
| SCHEMBL15185938 | 0.91 | NPY4R (0.51) | NPY4RNPY5RNPY1RNPY2RTLR2 | |
| SCHEMBL22821584 | 0.90 | NOD1 (0.54) | NPY4RNPY5RNPY1RNPY2RTLR2 | |
| SCHEMBL18796599 | 0.90 | NOD1 (0.54) | NPY4RNPY5RNPY1RNPY2RTLR2 | |
| SCHEMBL9666183 | 0.90 | NOD1 (0.54) | NPY4RNPY5RNPY1RNPY2RTLR2 | |
| SCHEMBL22806515 | 0.90 | NOD1 (0.54) | NPY4RNPY5RNPY1RNPY2RTLR2 | |
| SCHEMBL9664268 | 0.90 | NOD1 (0.54) | NPY4RNPY5RNPY1RNPY2RTLR2 | |
| SCHEMBL11347402 | 0.90 | NOD1 (0.54) | NPY4RNPY5RNPY1RNPY2RTLR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010053548-A2 | PTHR1 RECEPTOR COMPOUNDS | ANCHOR THERAPEUTICS, INC. (US) | 2010-05-14 | — | — | WO | disclosed |