Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 3/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | POLB | P06746 | 2/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | USP2 | O75604 | 1/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | PKM | P14618 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30736234 | 0.94 | HPGD (0.42) | HPGDKMT2ALMNAPOLBSMN1; SMN2 | |
| SCHEMBL28364585 | 0.87 | HPGD (0.49) | HPGDKMT2ALMNAPOLBSMN1; SMN2 | |
| SCHEMBL28038127 | 0.84 | KMT2A (0.44) | HPGDKMT2ALMNAPOLBSMN1; SMN2 | |
| SCHEMBL18598234 | 0.82 | LMNA (0.46) | HPGDKMT2ALMNAPOLBSMN1; SMN2 | |
| SCHEMBL23668692 | 0.81 | HPGD (0.47) | HPGDKMT2ALMNAPOLBSMN1; SMN2 | |
| SCHEMBL23691384 | 0.81 | HPGD (0.47) | HPGDKMT2ALMNAPOLBSMN1; SMN2 | |
| SCHEMBL23668701 | 0.81 | HPGD (0.47) | HPGDKMT2ALMNAPOLBSMN1; SMN2 | |
| SCHEMBL23668706 | 0.81 | HPGD (0.47) | HPGDKMT2ALMNAPOLBSMN1; SMN2 | |
| SCHEMBL29144661 | 0.81 | LMNA (0.45) | HPGDKMT2ALMNAPOLBSMN1; SMN2 | |
| SCHEMBL22235702 | 0.80 | HPGD (0.44) | HPGDKMT2ALMNAPOLBSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2015005901-A1 | COMBINATIONS OF HEPATITIS C VIRUS INHIBITORS | BRISTOL-MYERS SQUIBB COMPANY (US) | 2015-01-15 | — | — | WO | disclosed |
| WO-2013106520-A1 | HEPATITIS C VIRUS INHIBITORS | BRISTOL-MYERS SQUIBB COMPANY (US) | 2013-07-18 | — | — | WO | disclosed |