Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.60 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | ABCB1 | P08183 | 2/20 | 0.44 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.44 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.44 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.44 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.42 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | CCR5 | P51681 | 1/20 | 0.42 |
| ▸ | HTR2C | P28335 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16359786 | 1.00 | SIGMAR1 (0.60) | SIGMAR1ALDH1A1CYP3A4TSHRMAPT | |
| SCHEMBL19390631 | 1.00 | SIGMAR1 (0.60) | SIGMAR1ALDH1A1CYP3A4TSHRMAPT | |
| SCHEMBL2621398 | 0.92 | SIGMAR1 (0.55) | SIGMAR1ALDH1A1CYP3A4TSHRMAPT | |
| SCHEMBL129763 | 0.88 | SIGMAR1 (0.53) | SIGMAR1ALDH1A1CYP3A4TSHRMAPT | |
| SCHEMBL2621386 | 0.88 | SIGMAR1 (0.53) | SIGMAR1ALDH1A1CYP3A4TSHRMAPT | |
| SCHEMBL19139368 | 0.88 | SIGMAR1 (0.53) | SIGMAR1ALDH1A1CYP3A4TSHRMAPT | |
| SCHEMBL2621297 | 0.88 | SIGMAR1 (0.53) | SIGMAR1ALDH1A1CYP3A4TSHRMAPT | |
| SCHEMBL2621305 | 0.83 | SIGMAR1 (0.52) | SIGMAR1ALDH1A1CYP3A4TSHRMAPT | |
| SCHEMBL131871 | 0.83 | SIGMAR1 (0.52) | SIGMAR1ALDH1A1CYP3A4TSHRMAPT | |
| SCHEMBL2621307 | 0.83 | SIGMAR1 (0.52) | SIGMAR1ALDH1A1CYP3A4TSHRMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010054406-A1 | NOVEL LIPIDS AND COMPOSITIONS FOR THE DELIVERY OF THERAPEUTICS | ALNYLAM PHARMACEUTICALS, INC. (US) | 2010-05-14 | — | — | WO | disclosed |