Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FKBP1A | P62942 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19388394 | 0.95 | KMT2A (0.32) | SMN1; SMN2 | |
| SCHEMBL15114499 | 0.79 | SLC6A3 (0.33) | — | |
| SCHEMBL12928721 | 0.79 | KMT2A (0.30) | — | |
| SCHEMBL8283501 | 0.78 | EPHX1 (0.31) | — | |
| SCHEMBL38654851 | 0.75 | SLC6A3 (0.36) | — | |
| SCHEMBL15113784 | 0.75 | SLC6A3 (0.31) | — | |
| SCHEMBL7919980 | 0.73 | SMN1; SMN2 (0.32) | SMN1; SMN2 | |
| SCHEMBL16409160 | 0.73 | KMT2A (0.34) | SMN1; SMN2 | |
| SCHEMBL17816478 | 0.72 | HPGD (0.37) | SMN1; SMN2HSD17B10 | |
| SCHEMBL13769521 | 0.72 | NPC1 (0.31) | SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2015005901-A1 | COMBINATIONS OF HEPATITIS C VIRUS INHIBITORS | BRISTOL-MYERS SQUIBB COMPANY (US) | 2015-01-15 | — | — | WO | disclosed |
| WO-2013106520-A1 | HEPATITIS C VIRUS INHIBITORS | BRISTOL-MYERS SQUIBB COMPANY (US) | 2013-07-18 | — | — | WO | disclosed |