Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM2 | P08172 | 2/20 | 0.43 |
| ▸ | CHRM4 | P08173 | 2/20 | 0.43 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.43 |
| ▸ | CHRM3 | P20309 | 2/20 | 0.43 |
| ▸ | HTR3E | A5X5Y0 | 1/20 | 0.43 |
| ▸ | HTR3B | O95264 | 1/20 | 0.43 |
| ▸ | HTR3A | P46098 | 1/20 | 0.43 |
| ▸ | HTR3D | Q70Z44 | 1/20 | 0.43 |
| ▸ | HTR3C | Q8WXA8 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2621370 | 0.85 | SLC5A1 (0.50) | CHRM2CHRM4CHRM1CHRM3 | |
| SCHEMBL2621375 | 0.80 | RECQL (0.39) | CHRM2CHRM4CHRM1CHRM3 | |
| SCHEMBL9469882 | 0.79 | LGALS9 (0.46) | CHRM2CHRM4CHRM1CHRM3HTR3E | |
| SCHEMBL16299854 | 0.77 | PTPN1 (0.39) | CHRM2CHRM4CHRM1CHRM3 | |
| SCHEMBL26806110 | 0.75 | CHRNA7 (0.45) | CHRM2CHRM4CHRM1CHRM3HTR3E | |
| SCHEMBL11493141 | 0.73 | CHRM2 (0.41) | CHRM2CHRM4CHRM1CHRM3HTR3E | |
| SCHEMBL11608833 | 0.73 | CHRM2 (0.41) | CHRM2CHRM4CHRM1CHRM3HTR3E | |
| SCHEMBL11493146 | 0.73 | CHRM2 (0.41) | CHRM2CHRM4CHRM1CHRM3HTR3E | |
| SCHEMBL11088790 | 0.73 | CHRM2 (0.41) | CHRM2CHRM4CHRM1CHRM3HTR3E | |
| SCHEMBL11612057 | 0.73 | CHRM2 (0.41) | CHRM2CHRM4CHRM1CHRM3HTR3E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010054406-A1 | NOVEL LIPIDS AND COMPOSITIONS FOR THE DELIVERY OF THERAPEUTICS | ALNYLAM PHARMACEUTICALS, INC. (US) | 2010-05-14 | — | — | WO | disclosed |