Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HINT1 | P49773 | 1/20 | 0.40 |
| ▸ | STING1 | Q86WV6 | 1/20 | 0.32 |
| ▸ | NOS1 | P29475 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12261182 | 0.80 | PNP (0.40) | HINT1STING1 | |
| SCHEMBL12261233 | 0.80 | HPRT1 (0.41) | HINT1STING1 | |
| SCHEMBL12261202 | 0.77 | CYP3A4 (0.44) | HINT1 | |
| SCHEMBL12261197 | 0.76 | P2RY2 (0.47) | — | |
| SCHEMBL12261240 | 0.75 | CYP3A4 (0.38) | HINT1 | |
| SCHEMBL12261188 | 0.73 | CA12 (0.38) | HINT1 | |
| SCHEMBL12261177 | 0.71 | HINT1 (0.38) | HINT1 | |
| SCHEMBL12261217 | 0.70 | CYP3A4 (0.38) | HINT1 | |
| SCHEMBL16359333 | 0.69 | HINT1 (0.34) | HINT1 | |
| SCHEMBL12261205 | 0.69 | CYP3A4 (0.44) | HINT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010093608-A1 | CARBA-NUCLEOSIDE ANALOGS FOR ANTIVIRAL TREATMENT | GILEAD SCIENCES, INC. (US) | 2010-08-19 | — | — | WO | disclosed |